Stroke drug trial hopes to reduce disability with Anti-Inflammatory
NCT ID NCT07509645
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether adding tocilizumab, an anti-inflammatory drug, to standard emergency stroke treatment improves outcomes for people with a severe stroke in the back of the brain. About 348 adults will receive either tocilizumab or a placebo by IV right before a procedure to reopen blocked arteries. The main goal is to see if more people can function independently at 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tocilizumab (a drug that blocks interleukin-6, a protein involved in inflammation)
- What this could lead to
- If it works, this could lead to a new treatment that reduces disability after a severe stroke in the back of the brain.
- What could go wrong
- This is a mid-stage trial with 348 people, so results may not apply to all stroke patients. Tocilizumab can increase infection risk, and the benefit over standard care is unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anyang People's Hospital
RECRUITINGAnyang, Henan, 455000, China
Contact
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Capital Medical Univercity Xuanwu Hospital
RECRUITINGBeijing, 100053, China
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Lishui Central Hospital
RECRUITINGLishui, Zhejiang, 323000, China
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Nanyang Central Hospital
RECRUITINGNanyang, Henan, 473000, China
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People's Hospital of Linyi
RECRUITINGLinyi, Shandong, 276000, China
Contact
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People's Hospital of Xihua
RECRUITINGZhoukou, Henan, 466600, China
Contact
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People's Hospital of Yueqing
RECRUITINGYueqing, Zhejiang, 325600, China
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Suzhou Municipal Hospital
RECRUITINGSuzhou, Anhui, 234000, China
Contact
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Taizhou enze Hospital
RECRUITINGTaizhou, Zhejiang, 318000, China
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The First Affiliated Hospital of Henan Medical University
RECRUITINGXinxiang, Henan, 453000, China
Contact
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Xianyang First People's Hospital
RECRUITINGXianyang, Shanxi, 712000, China
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Yuncheng Central Hospital
RECRUITINGYuncheng, Shanxi, 044000, China
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Zibo Central Hospital
RECRUITINGZibo, Shandong, 255000, China
Contact
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