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Can the brain relearn balance after a stroke? a new study tracks the process

NCT ID NCT06727097

Knowledge-focused Sponsor: University of Cincinnati Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This study follows 45 people who have had their first ischemic stroke to see how their brains adjust to changes in sensory input, a process called sensory reweighting. Researchers will test balance and walking at several points over six months, and use brain scans to look for related structural changes. The goal is to understand how this reweighting affects walking ability and the risk of falls, which could inform future rehabilitation strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could point toward better ways to predict and prevent falls in stroke survivors, and guide rehabilitation that targets sensory reweighting.
What could go wrong
This is a small, early observational study, so it may not capture all the factors that influence recovery. The findings might not apply to people with more severe strokes or other types of brain injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2024

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Ischemic Stroke (unilateral, Supratentorial)

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. First ever clinical stroke 2. Stroke due to ischemia 3. Age 18 years or older 4. Ability to consent by patient (not surrogate), any time prior to acute hospital discharge Exclusion Criteria: 1. Pre-stroke dependence (modified Rankin Scale score of 3 or more) 2. Isolated brainstem or cerebellar stroke 3. Bilateral acute strokes 4. Co-enrollment in a trial of an intervention through six-month follow-up 5. Inability to maintain follow-up with study procedures through six-month follow-up 6. Contraindication to non-contrast MRI 7. Low likelihood of survival beyond the acute hospitalization, such as malignant cerebral edema 8. Pre-existing co-morbid conditions that significantly affects vision, somatosensory function, vestibular system, orthostasis, coordination or mobility 9. Post stroke mRS\>4 or discharge to hospice

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Cincinnati College of Medicine

    RECRUITING

    Cincinnati, Ohio, 45267, United States

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