Can early brain training and family coaching boost stroke recovery?
NCT ID NCT07793682
First seen Aug 28, 2026 · Last updated Sep 04, 2026 · Updated 2 times
Summary
This trial tests two early interventions for people who have had an ischemic stroke: a computerized cognitive training program for the patient and a psychoeducational program for the main caregiver. Both start about 20 days after hospital admission, much earlier than most rehabilitation trials. The goal is to see if these interventions improve the patient's quality of life and cognitive function, and reduce caregiver burden. The study uses a 2x2 factorial design, meaning it can test the effects of each intervention alone and together.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Computerized neuropsychological rehabilitation and family psychoeducational support
- What this could lead to
- If effective, this approach could improve quality of life and cognitive recovery after stroke, and ease the burden on family caregivers.
- What could go wrong
- The trial is small and early, so results may not apply broadly. The interventions may not outperform standard care, and the added effort for patients and caregivers could be a challenge.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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81 people
The number who actually took part.
- Started
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Nov 2025
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * First-ever ischemic stroke, excluding transient ischemic attack * Age 18 years or older * Inclusion within 96 hours of symptom onset * Functional independence before the index stroke, defined as a prestroke Modified Rankin Scale score ≤1 * Diagnosis of ischemic stroke classified according to the Oxfordshire Community Stroke Project as total anterior circulation infarction, partial anterior circulation infarction, posterior circulation infarction, or lacunar infarction * Capacity to provide written informed consent at enrollment or, in cases of temporary incapacity, availability of a legally authorized representative to provide consent on the participant's behalf, followed by participant re-consent if decision-making capacity is regained Exclusion Criteria: * Previous neurological or psychiatric disease associated with cognitive impairment * Severe systemic disease * Life expectancy of less than 1 year * Severe stroke, defined as a National Institutes of Health Stroke Scale score \>19 at admission * Alcohol or other substance abuse, excluding tobacco use * Clinically relevant aphasia preventing comprehension of neuropsychological test instructions, operationalized as a score \<5 on the fluency subscale of the Western Aphasia Battery * Sensory impairment preventing valid neuropsychological assessment or use of the intervention materials, such as severe visual or hearing impairment * Functional illiteracy, defined as inability to read and understand simple written instructions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Universitari Sant Joan de Déu de Manresa, Fundació Althaia
Manresa, Barcelona, 08243, Spain
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Other studies related to the condition(s) this trial covers.
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