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Which ventilator setting protects lungs best during prone surgery?

NCT ID NCT07680881

Knowledge-focused Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 02, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This study looks at two common ways to help patients breathe during surgery when they are lying face down (prone position). The goal is to see which method leads to less lung collapse (atelectasis) after the operation. Researchers will use lung ultrasound and oxygen measurements to compare the two ventilation modes in 90 adults having elective prone surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one ventilation method clearly reduces lung collapse, it could guide anesthesiologists in choosing safer breathing support during prone surgery.
What could go wrong
This is a small observational study, not a randomized trial, so it cannot prove cause and effect. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

90 people

The number who actually took part.

Started

Mar 2024

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 18 to 65 years with American Society of Anesthesiologists physical status I or II and a body mass index below 35 kg/m2, scheduled for elective surgery in the prone position at a single tertiary care hospital. Patients were grouped according to the intraoperative ventilation mode selected by the attending anaesthesiologist (volume-controlled ventilation or volume-controlled ventilation with Autoflow).

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Consented adults aged 18 to 65 years American Society of Anesthesiologists (ASA) physical status I or II Body mass index below 35 kg/m2 Scheduled for elective surgery in the prone position Oriented and cooperative Exclusion Criteria: No consent Pre-existing pulmonary disease Any perioperative lung pathology Inability to complete postoperative lung ultrasound assessment

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pulmonary complications Pulmonary atelectasis, postoperative

Contacts and locations

Locations

  • Cemil Tasciogu Research and Training Hospital

    Istanbul, Sisli, Turkey (Türkiye)

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