Double-Pronged cell therapy takes on tough lymphoma

NCT ID NCT07344818

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new type of cell therapy that uses a patient's own immune cells, engineered to attack two targets (CD19 and CD20) on lymphoma cells. It aims to see if this approach is safe for people with aggressive B-cell lymphoma that has come back or not responded to prior treatments. The study will enroll 18 adults and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CD19 and CD20 dual-target CAR-T cells (a type of immune cell therapy made from the patient's own blood)

What this could lead to

If it works, this could point toward a new treatment option for people with aggressive B-cell lymphoma that has not responded to standard therapy.

What could go wrong

This is a very early, small trial (18 people) focused on safety, not yet on effectiveness. The therapy may cause serious side effects or fail to control the cancer long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aggressive B-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••