Double-Pronged cell therapy takes on tough lymphoma

NCT ID NCT07344818

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new type of cell therapy that uses a patient's own immune cells, engineered to attack two targets (CD19 and CD20) on lymphoma cells. It aims to see if this approach is safe for people with aggressive B-cell lymphoma that has come back or not responded to prior treatments. The study will enroll 18 adults and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CD19 and CD20 dual-target CAR-T cells (a type of immune cell therapy made from the patient's own blood)
What this could lead to
If it works, this could point toward a new treatment option for people with aggressive B-cell lymphoma that has not responded to standard therapy.
What could go wrong
This is a very early, small trial (18 people) focused on safety, not yet on effectiveness. The therapy may cause serious side effects or fail to control the cancer long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China