New CAR-T therapy targets tough T-Cell cancers in early trial

NCT ID NCT06874946

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of CAR-T cell therapy that targets a protein called CD5 on cancer cells. It is for people with T-cell acute lymphoblastic leukemia or T-cell lymphoma that has come back or not responded to treatment. The trial has two phases: first, finding the safest dose, then testing how well it works in 30 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CD5-targeted CAR-T cells (a type of immune cell therapy)

What this could lead to

If successful, this could offer a new treatment option for people with hard-to-treat T-cell cancers that have not responded to standard therapies.

What could go wrong

This is an early-phase trial with only 30 participants, so results may not apply broadly. CAR-T therapy can cause serious side effects like cytokine release syndrome and neurological issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mature T-cell and NK-cell non-Hodgkin lymphoma peripheral T-cell lymphoma, not otherwise specified precursor T-cell acute lymphoblastic leukemia Precursor T-Cell Lymphoblastic Leukemia-Lymphoma T lymphoblastic leukemia/lymphoma T-cell acute lymphoblastic leukemia T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact