Can a shot keep hepatitis b away after 'Cure'? new trial aims to find out

NCT ID NCT07328711

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether hepatitis B immunoglobulin (HBIG) can help people with chronic hepatitis B stay virus-free after they've cleared the surface antigen (a key sign of cure). Researchers will give HBIG shots to 132 participants who already cleared the virus with standard therapy, then check if the virus stays gone for 48 weeks. The goal is to reduce relapse and find better ways to achieve a lasting cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hepatitis B immunoglobulin (HBIG)

What this could lead to

If it works, this could help people with chronic hepatitis B stay virus-free after initial clearance, reducing the chance of relapse and moving closer to a complete cure.

What could go wrong

This is a very early, small study (132 people) with no guarantee of success. HBIG is a temporary boost, not a permanent fix, and may not prevent relapse in the long run.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••