Could a simple scan and blood test outsmart liver cancer?

NCT ID NCT07764835

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study looks at whether a structured surveillance program using regular ultrasound and a blood test (alpha-fetoprotein) can detect liver cancer at an earlier, more treatable stage in people at high risk. About 300 adults with liver cirrhosis, chronic hepatitis B, or advanced liver fibrosis will be followed for up to 36 months. The goal is to see how often liver cancer is found, at what stage, and how quickly patients move from detection to treatment in real-world clinics.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Semiannual abdominal ultrasound (US LI-RADS) and alpha-fetoprotein (AFP) blood test
What this could lead to
If successful, this could improve early detection of liver cancer, leading to better outcomes for at-risk patients.
What could go wrong
This is an observational study, so it won't prove the surveillance program causes better outcomes. Also, the effectiveness depends on real-world adherence and may vary across centers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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