Can Weight-Loss surgery rewire the Liver's energy engine?
NCT ID NCT07760909
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study looks at how bariatric surgery affects the liver's energy processing in people with obesity and fatty liver disease. Researchers will use safe, non-radioactive tracer infusions and MRI scans before, during, and six months after surgery to measure changes in liver metabolism. The goal is to understand how these metabolic shifts relate to liver fat, stiffness, and disease severity, which could inform future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stable isotope tracer infusion (non-radioactive) and MRI/MRE imaging, alongside clinically indicated bariatric surgery
- What this could lead to
- If successful, this could reveal how bariatric surgery improves liver metabolism, potentially guiding better treatments for fatty liver disease.
- What could go wrong
- This is a small pilot study, so findings may not apply broadly. The procedures are complex and results depend on precise measurements.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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