A simple blood test may reveal how ewing sarcoma responds to therapy

NCT ID NCT07725783

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study tests whether changes in a blood protein called ProGRP can signal how well Ewing sarcoma is responding to treatment. Researchers will measure ProGRP levels in 100 newly diagnosed patients before, during, and after chemotherapy, then compare those levels with tumor size on scans. If ProGRP tracks with tumor changes, it could become a non-invasive way to monitor the disease. The blood test results are for research only and will not affect treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If ProGRP levels reliably reflect tumor response, doctors might one day use a simple blood test to monitor Ewing sarcoma treatment, reducing the need for frequent imaging.
What could go wrong
This is an early observational study, not a treatment trial. ProGRP may not correlate well with tumor changes, and results are for research only — they won't guide patient care during the study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital, Beijing, Beijing 100044

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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