New eye injection shows promise for wet AMD in everyday practice
NCT ID NCT07640997
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study will follow 300 people with wet age-related macular degeneration (nAMD) who receive aflibercept 8 mg injections as part of their routine care. Researchers want to see how well the drug improves vision and reduces retinal swelling over 12 months, and what side effects occur. The study includes both new and previously treated patients, and all treatment decisions are made by their own doctors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- aflibercept 8 mg (eye injection)
- What this could lead to
- If successful, this study could confirm that aflibercept 8 mg works well in everyday practice for treating wet age-related macular degeneration, potentially improving vision for many patients.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be less reliable. The drug is already approved, so the main question is about real-world effectiveness, not a breakthrough.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NEOVASCULAR AGE-RELATED MACULAR DEGENERATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Affiliated Hospital Of Zunyi Medical University
NOT_YET_RECRUITINGZunyi, Guizhou, China
-
Beijing CHAO-YANG Hospital, Capital Medical University
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
-
Beijing Friendship Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, China
-
Beijing Haidian Hospital
RECRUITINGBeijing, Beijing Municipality, China
-
Dalian No.3 People's Hospital
RECRUITINGDalian, Liaoning, China
-
Jinan Second People's Hospital
NOT_YET_RECRUITINGJinan, Shandong, China
-
Nanyang Eye Hospital
RECRUITINGNanyang, Henan, China
-
Ningbo Eye Hospital
NOT_YET_RECRUITINGNingbo, Zhejiang, China
-
Peking Union Medical College Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
-
Peking University First Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
-
Peking University People's Hospital
RECRUITINGBeijing, Beijing Municipality, 100044, China
-
Peking University Third Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, China
-
Qingdao Eye Hospital Of Shandong First Medical University
NOT_YET_RECRUITINGQingdao, Shandong, China
-
Shanghai Tenth People's Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, China
-
Shenzhen Eye Hospital
NOT_YET_RECRUITINGShenzhen, Guangdong, China
-
Sichuan Academy of Medical Sciences - Sichuan Provincial People's Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, China
-
TONG REN Hospital, Shanghai Jiao Tong University School Of Medicine
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, China
-
The 2nd Affiliated Hospital of Harbin Medical University
NOT_YET_RECRUITINGHarbin, Heilongjiang, China
-
The Affiliated Hospital of Inner Mongolia Medical University
NOT_YET_RECRUITINGHohhot, Inner Mongolia, China
-
The First Affiliated Hospital Of Fujian Medical University
NOT_YET_RECRUITINGFuzhou, Fujian, China
-
The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITINGWenzhou, Zhejiang, China
-
The Fourth People's Hospital Of Shenyang
NOT_YET_RECRUITINGShenyang, Liaoning, China
-
Tianjin Medical University Eye Hospital
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, China
-
Tianjin Medical University General Hospital
RECRUITINGTianjin, Tianjin Municipality, China
-
Tongji Hospital Tongji Medical College of HUST
NOT_YET_RECRUITINGWuhan, Hubei, China
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITINGWuhan, Hubei, China
-
Xi'an People's Hospital
NOT_YET_RECRUITINGXi'an, Shaanxi, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Longer-Lasting eye injection could cut treatment visits for macular disease
- Can a One-Time gene therapy tame wet AMD for years?
- Laser zap before eye injection could cut needle count for wet AMD
- Can a new eye injection save vision in wet AMD?
- Eye injection aims to tame leading causes of blindness
- Higher-Dose eye injection may help wet AMD patients who Didn't respond to standard treatments