New eye injection shows promise for wet AMD in everyday practice

NCT ID NCT07640997

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study will follow 300 people with wet age-related macular degeneration (nAMD) who receive aflibercept 8 mg injections as part of their routine care. Researchers want to see how well the drug improves vision and reduces retinal swelling over 12 months, and what side effects occur. The study includes both new and previously treated patients, and all treatment decisions are made by their own doctors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aflibercept 8 mg (eye injection)

What this could lead to

If successful, this study could confirm that aflibercept 8 mg works well in everyday practice for treating wet age-related macular degeneration, potentially improving vision for many patients.

What could go wrong

This is an observational study, not a controlled trial, so results may be less reliable. The drug is already approved, so the main question is about real-world effectiveness, not a breakthrough.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

wet macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital Of Zunyi Medical University

    NOT_YET_RECRUITING

    Zunyi, Guizhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing CHAO-YANG Hospital, Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Friendship Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Haidian Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dalian No.3 People's Hospital

    RECRUITING

    Dalian, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jinan Second People's Hospital

    NOT_YET_RECRUITING

    Jinan, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanyang Eye Hospital

    RECRUITING

    Nanyang, Henan, China

    Contact Phone: •••-•••-••••

  • Ningbo Eye Hospital

    NOT_YET_RECRUITING

    Ningbo, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University First Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University Third Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qingdao Eye Hospital Of Shandong First Medical University

    NOT_YET_RECRUITING

    Qingdao, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Tenth People's Hospital

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen Eye Hospital

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Academy of Medical Sciences - Sichuan Provincial People's Hospital

    NOT_YET_RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-••••

  • TONG REN Hospital, Shanghai Jiao Tong University School Of Medicine

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-••••

  • The 2nd Affiliated Hospital of Harbin Medical University

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Affiliated Hospital of Inner Mongolia Medical University

    NOT_YET_RECRUITING

    Hohhot, Inner Mongolia, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital Of Fujian Medical University

    NOT_YET_RECRUITING

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-••••

  • The First Affiliated Hospital of Wenzhou Medical University

    NOT_YET_RECRUITING

    Wenzhou, Zhejiang, China

    Contact Phone: •••-•••-••••

  • The Fourth People's Hospital Of Shenyang

    NOT_YET_RECRUITING

    Shenyang, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University Eye Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tongji Hospital Tongji Medical College of HUST

    NOT_YET_RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xi'an People's Hospital

    NOT_YET_RECRUITING

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••