GYNECOLOGIC CANCERS

This study compares two ways to close the vaginal vault after laparoscopic hysterectomy in women with gynecologic cancers. One method uses a self-locking barbed suture, the other a traditional braided suture. The goal is to see which leads to fewer complications like cuff tears, …

This study tests an experimental drug called IMGN151, alone or with other cancer treatments, in about 377 adults with gynecologic cancers like ovarian cancer. The goal is to check safety and find the best dose. Participants get the drug through an IV and will have regular check-u…

This study is for adults with certain cancers (like breast, lung, or ovarian) that are in complete remission but have persistently low platelet counts from past chemotherapy. It tests whether adding a vitamin A derivative (ATRA) to a standard platelet-boosting drug works better t…

This study tests a dye called CYTALUX (pafolacianine) that attaches to cancer cells and glows under a special camera during surgery. About 50 adults with certain cancers (like esophageal, pancreatic, or gynecologic) will get the dye before surgery. The goal is to see if the glowi…

This study tests whether an educational video and workbook can help gynecologic cancer patients bring up sexual health concerns with their cancer care team. About 200 patients will either receive the video and workbook plus a resource guide, or just the guide alone. Researchers w…

This study looks at two ways to close the surgical cut after gynecologic cancer surgery: using staples or separate stitches versus a continuous stitch under the skin. The goal is to see which method helps women feel better about their body image and mood. About 140 women will ans…

This study is testing an 8-week lifestyle program called HEAL-GYN for people who have finished chemotherapy for gynecologic cancer. The program focuses on healthy eating and physical activity to improve confidence, mental health, and overall well-being. Researchers will track cha…

This study is testing a virtual program called Mindful After Cancer (MAC) to help breast and gynecologic cancer survivors with sexual health and body image concerns. The program combines mindfulness training, educational materials, and group support over 8 weeks via video calls. …

This study tests a one-time educational session called Proactive Costs of Care, designed to help gynecologic cancer patients and their caregivers manage the financial side of treatment. A trained lay educator reviews health insurance, employment options, and community support usi…

This study is testing an online program called eSense-Cancer, designed to help people who have had gynecologic cancer with sexual health concerns. The program uses cognitive-behavioural therapy and includes 8 modules to be completed over 8-16 weeks. Researchers want to see if it …

This study compares three routine pain control methods used during minimally invasive cancer surgery: a nerve block plus local anesthetic, nerve block alone, or local anesthetic alone. About 48 adults having surgery for various cancers will be randomly assigned to one of the thre…

This study collects tumor and blood samples from 3,300 people at high genetic risk for breast, ovarian, and related cancers. Researchers want to learn how these cancers develop and how well treatments work. Participants include those with BRCA1/2 or other gene mutations, or a str…

This study follows 200 women with gynecologic cancer and their partners to see how sexual function changes over time. Researchers use questionnaires at diagnosis, 6 months, and 12 months after treatment. The goal is to understand when sexual counseling might be most helpful, with…

This study looks at whether hospitals in India are following standard guidelines for treating cervical cancer with radiation and chemotherapy. Researchers will review records from over 600 patients treated at multiple centers to see how often the recommended care is given. The go…