GYNECOLOGIC CANCERS

This study tests an experimental drug called IMGN151 for people with gynecologic cancers, including ovarian cancer. The drug is given alone or with other cancer treatments to see if it is safe and works. About 377 adults will take part at sites worldwide. The goal is to find bett…

This study tests whether adding a vitamin A-like drug (ATRA) to a platelet-boosting medication (romiplostim N01) works better than the platelet drug alone for cancer survivors whose platelet counts stay low after chemotherapy. About 220 adults with gynecologic, breast, or lung ca…

This study compares two types of stitches used to close the vaginal cuff after laparoscopic hysterectomy in women with gynecologic cancers. The goal is to see if a newer self-locking stitch reduces complications like infection, bleeding, or reopening of the cuff compared to tradi…

This study tests an FDA-approved drug called CYTALUX (pafolacianine) that makes cancer cells glow under a special camera during surgery. About 50 adults with certain gastrointestinal or gynecologic cancers will receive the drug before their operation. The goal is to see if the gl…

This study tests a one-time, 30-minute educational session with a trained educator to help gynecologic cancer patients and their caregivers manage the costs of care. The goal is to see if the program is practical and can boost confidence in handling financial issues while reducin…

This study is testing a virtual program called Mindful After Cancer (MAC) to help breast and gynecologic cancer survivors with sexual health and body image concerns. About 60 participants will be randomly assigned to either the 8-week MAC program or receive educational materials …

This study tests three common pain management methods used during minimally invasive cancer surgery. About 48 adults having surgery for cancers like liver, stomach, or colorectal cancer will be randomly assigned to one of three groups: a nerve block with numbing medicine, the ner…

This study tests an 8-week program called HEAL-GYN for people who have finished chemotherapy for gynecologic cancer. The program focuses on healthy eating and physical activity to improve confidence, mental health, and overall well-being. Researchers will measure changes in eatin…

This study is testing an online program called eSense-Cancer to help people who have had gynecologic cancer with sexual health issues. About 60 participants will use the program and report changes in sexual distress and satisfaction. The goal is to make support more accessible, e…

This study tests whether an educational video and workbook can help gynecologic cancer patients bring up sexual health concerns with their doctors. About 200 patients will either receive the video and a resource booklet, or just the booklet with usual care. Researchers will compa…

This study looks at two ways of closing the surgical cut after gynecologic cancer surgery: one using staples or separate stitches, and the other using a continuous stitch under the skin. The goal is to see which method helps women feel better about their body image and mood after…

This study follows 200 women with gynecologic cancer and their partners to see how their sexual function changes over time. Participants fill out questionnaires at diagnosis, 6 months, and 12 months after treatment. The goal is to understand these changes and find out when people…

This study looks at whether hospitals in India are following standard guidelines for treating cervical cancer with radiation and chemotherapy. Researchers will review records from over 600 patients across many hospitals to see how often the recommended treatment is given correctl…