Glow-in-the-Dark dye helps surgeons spot hidden cancer

NCT ID NCT07039526

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a dye called CYTALUX (pafolacianine) that attaches to cancer cells and glows under a special camera during surgery. About 50 adults with certain cancers (like esophageal, pancreatic, or gynecologic) will get the dye before surgery. The goal is to see if the glowing helps surgeons find and remove tumors that are not visible under normal light. Participation lasts about 2 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pafolacianine (CYTALUX)

What this could lead to

If it works, this could help surgeons see and remove more cancer during surgery, potentially improving outcomes.

What could go wrong

This is a small early-phase study (50 people) testing an already-approved drug for a new use. It may not work for all cancer types, and the dye could cause allergic reactions or false positives.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

digestive system cancer digestive system neoplasm esophageal cancer Esophageal Neoplasms female reproductive organ cancer hepatobiliary neoplasm malignant pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clemments University Hospital

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact