New pill targets Hard-to-Treat cancers with PIK3CA mutation
NCT ID NCT07524322
First seen Apr 14, 2026 · Last updated May 15, 2026 · Updated 7 times
Summary
This early-phase study tests an experimental oral drug, RGT-490, in adults with advanced solid tumors (including breast, ovarian, and endometrial cancers) that have a specific genetic change called PIK3CA. The main goals are to check the drug's safety, find the right dose, and see if it shrinks tumors. About 63 participants whose cancer has worsened after standard treatments will take the drug daily.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NEXT Houston
RECRUITINGHouston, Texas, 77054, United States
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NEXT San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Conditions
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