HPV Vaccine's Real-World impact under the microscope in sikkim

NCT ID NCT04588402

Recruiting now Prevention Sponsor: International Agency for Research on Cancer Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study checks how well the HPV vaccine prevents cervical HPV infection in women in Sikkim, India, about 7 years after the vaccine was introduced. Researchers will collect cervical samples from 5,500 married women aged 18-22 and compare infection rates to those before vaccination. The goal is to see if the vaccine is working in real life and provide feedback to health authorities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could show that the HPV vaccine effectively prevents cervical HPV infection in a real-world setting, supporting its use in public health programs.
What could go wrong: This is an observational study, not a controlled trial, so results may be influenced by other factors. It only measures infection, not cancer prevention, and is limited to one region.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms human papilloma virus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER

Contacts and locations

Locations

Sikkim Manipal Hospital
RECRUITING

Gangtok, Sikkim, 737107, India

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