Light may spot cervical cancer before it spreads

NCT ID NCT00900575

Recruiting now Diagnosis Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether special light-based devices can detect cervical cancer by identifying unique optical signatures of abnormal tissue. Researchers will use three different devices—a bench-top spectrometer, a portable spectrometer, and a pocket-sized colposcope—on 350 women already scheduled for colposcopy, LEEP, or follow-up Pap smears. The goal is to see if these tools can accurately spot cervical dysplasia without needing a biopsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a faster, non-invasive way to detect cervical cancer during a routine exam.
What could go wrong: This is an early-stage study focused on finding light patterns, not yet proving the device works in real-world screening. Results may not lead to a commercial test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER

Contacts and locations

Locations

Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States

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