Could a simple estrogen treatment sharpen the view for cervical cancer screening?

This trial tests whether applying vaginal estrogen before a colposcopy helps doctors see the cervix more clearly in women aged 50 and older. As women age, the area where precancerous changes occur can become harder to view, which may lead to missed diagnoses or repeat procedures. Half of the participants will receive estrogen and half a placebo before their exam, and the study will compare how well the transformation zone is visualized and biopsied. The goal is to see if this simple step can make cervical cancer diagnosis more accurate and timely.