University Of Aarhus

This study tests whether nurse-led telehealth support helps people with gout stick to their medication and keep uric acid levels under control. About 200 adults from Denmark who already take gout medication will be randomly assigned to either receive extra nurse support (via app,…

This study looks at whether using aspirin alone is as effective and safer than using aspirin with another blood thinner (fondaparinux) before a heart procedure in people with a certain type of heart attack (NSTEMI). About 5,000 participants will be randomly assigned to one of the…

This study looks at children aged 5 to 14 who take medicine for urinary incontinence (like bedwetting) and are ready to stop. It compares stopping the medicine all at once versus slowly tapering off, to see which method lowers the chance of symptoms coming back. The goal is to fi…

This study tests whether using a fluorescent dye called indocyanine green (ICG) during surgery helps surgeons see and remove sarcoma tumors more completely. About 90 adults with intermediate-to-high grade sarcoma of the trunk or limbs will take part. The goal is to reduce the num…

This study looks at whether opening narrowed kidney arteries with a small mesh tube (stent) helps high-risk patients with resistant high blood pressure, worsening kidney function, or heart failure. About 80 participants will either get the stent procedure or a sham procedure, whi…

This study looks at whether DNA markers in urine, vaginal, and cervical samples can accurately predict endometrial cancer risk in women with postmenopausal bleeding. About 600 participants will provide samples and undergo standard ultrasound. The goal is to find a less invasive w…

This study tests a special MRI designed for dentistry to see if it can diagnose jaw joint disorders, tooth infections, and help plan dental implants as well as or better than traditional X-rays. About 470 adults who need dental imaging will get both an MRI and standard X-rays, an…

This study is testing whether DNA changes in urine and vaginal samples can accurately detect endometrial cancer. Researchers will compare samples from 120 women—half with diagnosed cancer and half healthy—to see if this simple, patient-friendly method works. If successful, it cou…

This study is testing whether offering liver cancer screening every 6 months to people with cirrhosis can reduce deaths from liver cancer. About 617 participants in one region of Denmark will get an ultrasound and blood test. Their outcomes will be compared to similar patients in…

This study tests a new digital follow-up program for people who had early-stage colorectal cancer. The program uses a smartphone app to monitor symptoms, fear of cancer returning, and late side effects, and provides personalized care. It compares this approach to standard follow-…

This study looks at whether adding progressive resistance training to a patient education program helps people with hip osteoarthritis feel better and move easier. 150 adults with hip OA will be randomly assigned to either education plus exercise or education alone. Researchers w…

This study tests whether using a SPECT scan to guide radiation therapy can reduce lung damage in people with advanced lung cancer. About 90 patients receiving chemo-radiation will be randomly assigned to standard or SPECT-guided planning. The goal is to see if avoiding highly fun…

This study tests whether a program of exercise and patient education can reduce hip and groin pain in people with hip dysplasia compared to usual care. About 200 adults with confirmed hip dysplasia and at least three months of pain will take part. The main goal is to see if pain …

This study looks at how to best combine two common therapy techniques—changing negative thoughts and practicing detached mindfulness—for people with anxiety or depression. Researchers want to find out if using them together, alone, or in a specific order works better. About 93 ad…

This study tests whether a supplement called tributyrin can help lower blood sugar and reduce appetite in people with overweight or obesity. Twelve participants will take either the supplement or a placebo for two weeks, then switch. Researchers will measure blood sugar, hunger, …

This study tests whether a therapist-guided exercise program helps people aged 50 and older recover better from a wrist fracture compared to standard advice. Participants will either receive supervised exercise sessions plus usual care, or usual care alone. The main goal is to se…

This study tests whether fecal microbiota transplantation (FMT) capsules can help people with diarrhea and colitis caused by immune checkpoint inhibitors, a common side effect of cancer treatment. Twenty adults with melanoma or kidney cancer will receive either FMT or placebo cap…

This study tests whether combining two drugs (solifenacin and mirabegron) at low doses works better than high doses of either drug alone for children aged 5 to 14 with overactive bladder and daytime wetting. About 236 children who did not fully respond to low-dose single drugs wi…

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial weakness after a first-time stroke. Researchers will measure changes in facial symmetry using video recordings. The trial aims to recruit 130 adul…

This study looks at whether a 12-week progressive resistance exercise program can help reduce chronic pain in people with multiple sclerosis. 116 participants will be randomly assigned to either the exercise group or a waitlist group receiving usual care. The goal is to see if ex…

This study looks at how well spinal cord stimulation works for people with long-term pain. About 25 adults who already have a spinal cord stimulator will rate their pain with the device on and off. The goal is to see if the stimulation truly reduces pain compared to a placebo eff…

This study follows 250 people with chronic diverticular disease to see if elective surgery improves their quality of life compared to those who continue with non-surgical care. Participants complete questionnaires about their symptoms, bowel function, and overall well-being. The …

This study looks at how the way treatment information is given affects how well migraine medication works and what side effects people notice. Researchers will give 128 adults with episodic migraine six different treatments in a random order to compare drug effects, placebo effec…

This study aims to confirm that a blood test detecting tumor DNA after colorectal cancer surgery can better predict the risk of cancer returning than current methods. Researchers will follow 1,600 patients who had surgery for stage I-III colorectal cancer to see if the test resul…

This study looks at how the hormone glucagon works in people with type 2 diabetes, especially those who also have fatty liver disease. Researchers want to know if glucagon resistance makes liver and heart problems worse. Participants will have scans, blood tests, and fat biopsies…

This study looks at how the tissue in a leg amputation stump heals in people with and without diabetes. Researchers will use a small probe (microdialysis) to measure chemicals that show blood flow, inflammation, and infection risk. The goal is to understand why healing differs be…

This study looks at whether low-dose vaginal estrogen, used to treat vaginal dryness in postmenopausal women, changes blood clotting factors. Researchers will take blood samples before and after 3 months of treatment in 90 women, some with a history of blood clots. The goal is to…

This study is for people with lung or chest cancers that have come back or are new, and who have already had radiation before. Researchers want to see how safe and effective a second round of high-dose radiation is by tracking side effects and survival in 500 participants. The go…

This study watches how breathing support (ventilation) is given during CPR for adults whose heart stops in the hospital. It aims to find which air volume and breathing rate work best to restart the heart. Researchers will compare different ventilation levels to see which leads to…

This study looks at how blood sugar levels change in pregnant women with gestational diabetes and how those changes relate to baby growth and birth outcomes. About 100 women will wear a continuous glucose monitor for 14 days to track their sugar patterns. The goal is to better un…

This observational study looks at whether a combination of treatments can lower the oxygen demand of the heart and kidneys in people with type 1 diabetes. Researchers will compare those receiving intensive care to those on standard treatment. Forty adults with long-standing type …

This study looks at how often people with Crohn's disease, ulcerative colitis, an ileostomy, or bile acid diarrhea have low magnesium levels. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. Researchers will compare dif…

This study looks at whether doing a membrane sweep several times near the end of pregnancy helps labor start naturally before 41 weeks and 3 days. About 1,500 pregnant women will either get no sweeps or up to three sweeps a few days apart. The goal is to see if this simple proced…

This study is a Danish national registry that will follow 160 high-risk patients with resistant hypertension and blocked kidney arteries who undergo a procedure called percutaneous transluminal renal angioplasty (PTRA) to open the blockage. The main goal is to measure changes in …

This study looks at how often blood vessel problems happen after a kidney transplant and whether a balloon treatment can help. Researchers will follow 60 kidney transplant patients in Denmark to check kidney function and blood pressure. The goal is to find better ways to diagnose…

This study aims to see how faithfully people with bipolar disorder take their lithium medication in real life. About 50 participants will use a special pillbox that records when they remove a pill, and they will get weekly phone calls to compare their reported intake with the rec…

This study aims to understand the sexual health challenges faced by bladder cancer patients and develop a support program. Researchers will interview 30 patients to learn about their needs and preferences. The goal is to create a tailored intervention to improve sexual well-being…

This study aims to find out if spinal cord stimulation (SCS) truly reduces pain or if the relief comes from patients' expectations. Twenty-five adults who already have an SCS implant for chronic pain will take part in four test sessions. During each session, the device is turned …

This study looks at how ketone bodies—chemicals your liver makes when you fast or exercise—affect energy use and insulin sensitivity. Ten overweight adults aged 55-70 will receive different combinations of ketone supplements, growth hormone, or placebo on four separate days. Rese…

This study looks at whether regular patient questionnaires and a special blood test (circulating tumor DNA) can detect vulva cancer recurrence earlier than standard follow-up. About 295 women with vulva cancer will be followed for two years, and their results will be compared to …

This study looks at how different sex hormone levels affect muscle growth from exercise in women. Researchers will compare women with natural cycles, those using hormonal IUDs, and those on hormonal birth control. The goal is to understand how hormones influence muscle, fat, and …

This study watches how the steroid dexamethasone moves through the body and affects bone health in 100 children (ages 1-17) being treated for acute lymphoblastic leukemia. Researchers will measure drug levels in blood and spinal fluid, track bone density with scans, and check for…

This study looks at whether experiencing a small time delay every day can change your internal body clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples who live together. The goal is to understand how our daily routines affect sleep and circa…

This study watches 250 adults who remain unconscious after a cardiac arrest to see if early brain tests can predict when they will wake up. Researchers use EEG, pupil checks, and ultrasound to find clues. The goal is to help doctors know sooner who will recover, but this study do…

This study looks at two common drugs used to manage blood pressure during brain surgery. The goal is to find out which one does a better job keeping blood and oxygen flowing to the brain and other organs. About 32 adults having brain tumor surgery will take part. The results will…

This study involves 60 adults with chronic migraine to understand how drug and placebo responses interact during treatment. Participants will receive four different treatment conditions in a random order, and researchers will measure headache intensity, migraine days, and side ef…

This study looks at whether being a morning person or an evening person changes how you experience time. Healthy Danish adults aged 23-45 who are clearly one type will do computer tasks at their best time and at a mismatched time. The goal is to see if time judgments and alertnes…

This study looks at how your internal body clock changes the way you perceive time, think, and feel when you stay awake for 36 hours. Thirty healthy adults aged 23 to 45 will stay in a controlled lab, awake the whole time, with constant light, posture, food, and activity. Every t…

This study looks at whether adding an MRI scan to the usual CT scan helps doctors choose the right treatment for people with pancreatic cancer. About 200 patients whose CT scans show no spread to the liver will be randomly assigned to get an MRI or not. The goal is to see if the …