Simple blood test could spare thousands from unnecessary chemo

NCT ID NCT06076811

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a blood test for tumor DNA can better predict if colorectal cancer will come back after surgery. Currently, doctors use tumor tissue to decide who needs chemotherapy, but many patients get chemo they may not need. The test checks for cancer DNA in the blood, which could be a more accurate way to find hidden cancer cells. Researchers will follow 1,600 patients to see if the test works in real-world practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

liquid biopsy (circulating tumor DNA test)

What this could lead to

If successful, this blood test could become a standard way to identify which colorectal cancer patients need chemotherapy after surgery, sparing others from unnecessary side effects.

What could go wrong

This is an observational study, not a treatment trial. The test may not prove more accurate than current methods, and results may not change practice immediately.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal cancer colorectal carcinoma colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University Hospital

    RECRUITING

    Aalborg, North Denmark, 9000, Denmark

    Contact Email: •••••@•••••

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Central Jutland, 8000, Denmark

    Contact Email: •••••@•••••

  • Bispebjerg Hospital

    RECRUITING

    Copenhagen, Capital Region of Denmark, 2400, Denmark

    Contact Email: •••••@•••••

  • Gødstrup Hospital

    RECRUITING

    Herning, Central Jutland, 7400, Denmark

    Contact Email: •••••@•••••

  • Herlev Hospital

    NOT_YET_RECRUITING

    Herlev, Capital Region of Denmark, 2730, Denmark

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Odense University Hospital

    RECRUITING

    Odense, The Region of Southern Denmark, 5000, Denmark

    Contact Email: •••••@•••••

  • Regional Hospital Horsens

    RECRUITING

    Horsens, Central Jutland, 8700, Denmark

    Contact Email: •••••@•••••

  • Regional Hospital Randers

    RECRUITING

    Randers, Central Jutland, 8930, Denmark

    Contact Email: •••••@•••••

  • Regional Hospital Viborg

    RECRUITING

    Viborg, Central Jutland, 8800, Denmark

    Contact Email: •••••@•••••

  • Vejle Hospital

    RECRUITING

    Vejle, 7100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••