Can we predict chemo brain before it happens?
NCT ID NCT05014399
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This study looks at how chemotherapy for colon or rectal cancer affects thinking and memory. Researchers will track changes in brain function and blood proteins in 60 patients during and after treatment. The goal is to find tests that could identify who is at risk for 'chemo brain' and help manage these side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cytotoxic chemotherapy
- What this could lead to
- If successful, this could lead to better ways to identify patients at risk for chemo-related memory and thinking problems, enabling earlier support and interventions.
- What could go wrong
- This is an observational study with a small number of participants, so findings may not apply to all patients. It does not test a treatment, so it won't directly improve cognitive function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Parkview Cancer Institute
RECRUITINGFort Wayne, Indiana, 46845, United States
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