COGNITIVE CHANGE

This study works with 300 Native American elders aged 50 and older who have sleep apnea and a PAP machine. It tests if adding motivational interviews and text messages to usual care helps them use their machine more often. The goal is to improve sleep apnea control and possibly l…

This study tests an online educational program called Brain Health PRO in 700 Canadians at risk for dementia. Participants are randomly assigned to start the 6-month program immediately or after a 6-month delay. The program covers lifestyle factors like diet, exercise, sleep, and…

This study tests whether combining the drug memantine with a structured exercise program can improve memory and thinking problems (often called 'chemo brain') in women with early-stage breast cancer undergoing chemotherapy. Ninety participants will be split into three groups: mem…

This study tests whether adjusting the electrical amplitude of ECT (electroconvulsive therapy) to each person can better treat depression and reduce memory problems. Researchers will compare a personalized amplitude approach to the standard fixed 800 mA setting in 50 older adults…

This study tests whether a 16-week high-intensity interval training (HIIT) program on a stationary bike can improve thinking, memory, and heart health in women undergoing chemotherapy for breast cancer. Thirty participants will be randomly assigned to either HIIT or a stretching …

This study tests whether a technique called high-definition transcranial direct current stimulation (HD-tDCS) can improve word-finding difficulties in people who had a traumatic brain injury at least a year ago. The device delivers a very low electrical current through electrodes…

This study from Stanford University is looking at how a 6-week math training program changes brain activity and thinking skills in children with math learning disabilities (dyscalculia). About 180 children aged 6-12 will do math problems on a tablet at home and get weekly one-on-…

This study looks at whether people aged 70 and older experience changes in thinking skills, like attention and processing speed, after same-day hip or knee replacement surgery. About 48 participants will take a short cognitive test before surgery and again on the first and sevent…

This study checks whether keeping indoor temperatures at 26°C is enough to protect young, habitually active adults from heat stress. Ten healthy volunteers aged 18-29 will spend 8 hours in a controlled warm room, either resting or doing light exercise while wearing extra clothing…

This study will enroll 1,600 healthy adults (ages 18-30 or 60-85) to see if doing computer-based cognitive tasks—like remembering sequences or spotting patterns—can improve memory, attention, and thinking skills. Participants will complete up to 15 hours of tasks over 4-8 weeks. …

This study looks at how neoadjuvant chemotherapy (given before surgery) affects thinking skills like memory and attention in people with advanced ovarian cancer. Researchers will test 18 participants using questionnaires and cognitive tests over about 10 months. The goal is to be…

This study looks at how being in a hot room affects the body, thinking, and mood of people with schizophrenia. Ten adults with and without schizophrenia will sit in a warm or very hot room for six hours, doing light activity. The goal is to learn how heat impacts them so we can c…

This study looks at whether keeping indoor temperatures at 26°C can prevent dangerous heat strain and mental fog in children aged 10-15 during a simulated school day. Ten kids will be exposed to both a mild (26°C) and a hot (36°C) room while their body temperature and mood are me…

This study explores how aging affects the ability to learn who to trust. Researchers will use real-time fMRI to give older adults feedback on their brain activity while they practice trust-related tasks. The goal is to see if this brain training can improve their decision-making …

This study looks at whether a 6-month cardio-dance fitness program can improve brain health and lower Alzheimer's risk in 280 older African Americans (age 60+). Participants will do either dance fitness or strength/flexibility exercises three times a week. Researchers will measur…

This study is testing different types of computer-based brain training in 780 teenagers, some with ADHD and some without. The goal is to find out which training methods—like adding game elements or varying the number of tasks—work best for improving memory and focus. Participants…

This study tests whether spending less time in bed for four weeks can deepen sleep and boost memory in adults aged 65-85 who have poor sleep and are at risk for Alzheimer's. Researchers will measure brain activity, memory, and blood markers. The goal is to see if a simple behavio…

This research study looks at how practicing certain visual tasks can improve cognitive abilities like attention and reading. Healthy adults aged 18-30 and 60-85 will complete computer-based training over several weeks. The goal is to understand how training changes the way we see…

This study tests whether a 14-day mobile diary is a practical way to measure daily stress and thinking (cognitive) changes in breast cancer survivors. Researchers will enroll 30 racially diverse women aged 40 and older who are at least five years past diagnosis. Participants comp…

This study follows 65 adults with obstructive sleep apnea to see how three weeks of CPAP therapy changes their thinking skills, blood markers of brain health, and emotional well-being. Participants complete memory and attention tests, give blood samples, and fill out questionnair…