COGNITIVE CHANGE

This study is testing a culturally tailored support program to help Native American elders aged 50+ use their sleep apnea machines more consistently. Researchers want to see if better machine use can improve thinking skills and potentially lower the risk of Alzheimer's disease. P…

This study is testing a new way to adjust the electrical dose used in Electroconvulsive Therapy (ECT) for severe depression. Researchers want to see if customizing the dose for each person can improve depression relief while causing fewer memory and thinking problems compared to …

This study is testing whether a simple sleep improvement program can help slow down brain changes linked to Alzheimer's disease. Researchers will work with 116 older adults who have mild memory concerns or are at risk for Alzheimer's. For four weeks, participants will follow a sc…

This study is testing whether a six-month cardio-dance fitness program can improve brain health and reduce the risk of Alzheimer's disease in older African Americans. Researchers will compare the dance program to a strength and balance program in 280 sedentary adults aged 60 and …

This study is testing whether a gentle, non-invasive brain stimulation technique can help people who have trouble finding words after a traumatic brain injury (TBI). Researchers will use a special cap to deliver a tiny electrical current to specific brain areas involved in memory…

This study is testing if a drug called memantine, combined with a supervised exercise program, can help reduce memory and thinking problems ('chemo brain') during breast cancer chemotherapy. It will involve 90 women with early-stage breast cancer who are already reporting mild co…

This study is testing whether a 16-week high-intensity interval training (HIIT) exercise program can help improve memory, focus, and thinking skills in women undergoing chemotherapy for breast cancer. Researchers will compare the exercise group to a control group doing gentle str…

This study aims to test a simple method for understanding the daily lives of breast cancer survivors. Researchers want to see if a 14-day mobile phone diary is a practical way to track daily stress and thinking patterns. They will recruit 30 diverse survivors who are at least fiv…

This study aims to understand if keeping indoor temperatures at 26°C protects children from heat-related physical strain and cognitive decline. Researchers will compare how 10 children, aged 10-15, respond physically and mentally during a simulated 6-hour school day in a 26°C roo…

This study aims to find out if practicing specific computer-based thinking tasks can improve skills like memory, attention, and problem-solving. It will enroll 1,600 participants who will be randomly assigned to different training groups. Participants will complete a series of sh…

This research study aims to understand how different types of visual practice or 'training' can improve how people see and process information. It will enroll about 1,140 healthy adults, split between younger (18-30) and older (60-85) age groups, to test which of 12 different com…

This study aims to understand which types of brain training work best to improve memory, focus, and thinking skills in teenagers, including those with ADHD. Researchers will test six different training setups with 780 adolescents over 4 weeks to see which methods are most effecti…

This study aims to understand how a standard sleep apnea treatment (ventilotherapy) affects patients' thinking skills, brain health markers, and overall well-being. Researchers will observe 65 adults with sleep apnea, measuring their memory, attention, mood, and blood markers bef…

This study aims to understand how chemotherapy affects memory and thinking skills in women with advanced ovarian cancer. Researchers will follow 18 patients for about 10 months, testing their cognitive function before, during, and after treatment. The goal is to measure changes i…

This study aims to understand how hot indoor temperatures affect people with schizophrenia. Researchers will compare a comfortable room (26°C) to a very hot room (36°C) while measuring participants' body temperature, heart function, thinking skills, and mood. The goal is to gathe…

This study aims to find out if the recommended indoor temperature limit of 26°C (79°F) is enough to protect healthy, active young adults from physical strain during a hot day. Researchers will measure body temperature, heart strain, and thinking skills in 10 young adults during a…