COGNITIVE CHANGE

This phase 2 study tests whether a plant-based supplement called PhytoSERM can help prevent the drop in brain activity and thinking skills that often happens during menopause. The trial includes 100 women aged 45-60 who are in early menopause and have hot flashes. Participants ta…

This study looks at whether osteopathic manipulation, a hands-on treatment for pain, can also improve thinking problems like memory and attention in adults with pain. About 100 people aged 40 and older with neck, back, or shoulder pain and self-reported thinking issues will take …

This study looks at how two different snacks—one with honey and nuts, the other with sugar and nuts—affect blood sugar levels in healthy pre-menopausal women. Researchers want to see if honey and nuts together can keep blood sugar more stable after eating, while also helping with…

This study looks at whether people with atrial fibrillation (an irregular heart rhythm) experience temporary changes in thinking, memory, or focus during an episode. Researchers will test 600 participants using tablet-based games that measure cognitive skills, comparing their per…

This study is creating a large database of information from 250 older adults (65+) having surgery with anesthesia. Researchers will collect questionnaires, blood samples, brain wave recordings, and memory tests before and up to a year after surgery. The goal is to find patterns t…

This study will enroll 100,000 adults aged 45 and older to track early signs of Alzheimer's and Parkinson's disease using phone apps, voice recordings, and movement tests. Researchers aim to create better tools for early diagnosis by combining digital data with genetic and biolog…

This study looks at how memory and thinking skills change after hip or knee replacement surgery. Researchers will test 505 adults aged 50 and older before and after surgery to see how many experience cognitive decline. The goal is to identify risk factors and better understand ho…

This study aimed to understand how blood pressure changes when standing up affect thinking skills and brain blood flow in people with Parkinson's disease. Researchers planned to compare those with and without orthostatic hypotension (low blood pressure upon standing) using cognit…