Brain fog after hip or knee replacement: how common and how long?

NCT ID NCT03147937

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 505 adults aged 50 and older who are having hip or knee replacement surgery. Researchers use a simple online card-game test to measure changes in memory, attention, and thinking before and up to 4.5 months after surgery. The goal is to find out how many people experience lasting cognitive decline and what factors might increase that risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify who is at risk for long-term thinking problems after surgery and point toward ways to prevent them.

What could go wrong

This is an observational study, not a treatment trial. It measures changes but does not test any intervention, so it cannot directly improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disease cognitive disorder Cognitive Dysfunction delirium Inflammation inflammatory disease Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada