Menopause brain fog: new supplement shows promise in clinical trial

NCT ID NCT05664477

First seen Mar 22, 2026 · Last updated May 14, 2026 · Updated 7 times

Summary

This phase 2 study tests whether a plant-based supplement called PhytoSERM can help prevent the drop in brain activity and thinking skills that often happens during menopause. The trial includes 100 women aged 45-60 who are in early menopause and have hot flashes. Participants take either PhytoSERM or a placebo, and researchers measure brain metabolism using PET scans and cognitive tests.

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Contacts and locations

Locations

  • The Alzheimer's Prevention Program / Weill Cornell Medicine

    New York, New York, 10021, United States

  • University of Arizona / Clinical & Translational Sciences Research Center (CATS

    Tucson, Arizona, 85721, United States

Conditions

Explore the condition pages connected to this study.