Gut bacteria may soothe menopause symptoms — a trial puts it to the test

NCT ID NCT07759908

Completed Symptom relief Sponsor: University College Cork Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a daily synbiotic supplement, combining probiotics and a prebiotic fiber, can ease common perimenopause and menopause symptoms like poor sleep, anxiety, and brain fog. Women aged 44–55 experiencing these symptoms will take either the active supplement or a placebo for 8 weeks. The study also looks at effects on gut and vaginal health, offering a potential natural, non-hormonal approach to support women during this transition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FemmeBiome Meno, a synbiotic supplement containing probiotics and prebiotics
What this could lead to: If it works, this could offer a natural, non-hormonal option to ease common menopause symptoms like sleep problems, anxiety, and brain fog.
What could go wrong: This is a small, early trial, and the specific blend hasn't been studied before. Results may not generalize, and benefits could be modest or absent.

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Conditions

The condition(s) this trial relates to.

anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENOPAUSE PERIMENOPAUSAL WOMEN PERIMENOPAUSE

Contacts and locations

Locations

Atlantia Clinical Trials

Cork, Ireland

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