Can tailoring ECT strength boost mood and spare memory?
NCT ID NCT05699226
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adjusting the electrical amplitude of ECT (electroconvulsive therapy) to each person can better treat depression and reduce memory problems. Researchers will compare a personalized amplitude approach to the standard fixed 800 mA setting in 50 older adults with depression. Participants will have their depression severity and cognitive function measured before and after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Soterix Medical Incorporated 4x1 adapter (device) and traditional ECT device
What this could lead to
If successful, this could lead to a more personalized ECT approach that reduces memory side effects while still treating depression effectively.
What could go wrong
This is a small early-stage study with only 50 participants, so results may not apply to everyone. The individualized amplitude approach may not show clear benefits over standard ECT.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of New Mexico Health Science Center
RECRUITINGAlbuquerque, New Mexico, 87110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••