ECT
Clinical trials for ECT explained in plain language.
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Can a reversal drug protect memory during ECT for depression?
Symptom relief Recruiting nowThis study tests whether giving flumazenil, a drug that reverses the effects of benzodiazepines, right before electroconvulsive therapy (ECT) can reduce cognitive side effects like memory loss in hospitalized patients with depression. About 145 participants will either continue t…
Matched conditions: ECT
Phase: NA • Sponsor: Anders Jørgensen • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can tailoring ECT strength boost mood and spare memory?
Symptom relief Recruiting nowThis study tests whether adjusting the electrical amplitude of ECT (electroconvulsive therapy) to each person can better treat depression and reduce memory problems. Researchers will compare a personalized amplitude approach to the standard fixed 800 mA setting in 50 older adults…
Matched conditions: ECT
Phase: NA • Sponsor: University of New Mexico • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Could a simple drug boost ECT for depressed teens?
Symptom relief Recruiting nowThis study tests whether adding a low dose of esketamine (a fast-acting anesthetic) to standard electroconvulsive therapy (ECT) can improve depression outcomes in adolescents aged 13-17 with severe depression. About 220 participants will be randomly assigned to receive either esk…
Matched conditions: ECT
Phase: EARLY_PHASE1 • Sponsor: Min Su • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC