Leukemia Drug's bone risk under the microscope

NCT ID NCT06367725

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the steroid dexamethasone, used to treat childhood acute lymphoblastic leukemia, affects bone density and the nervous system. Researchers will measure drug levels in blood and spinal fluid, and track bone loss and nerve-related side effects. The goal is to find ways to reduce these side effects in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If successful, this study could help doctors understand how to adjust dexamethasone doses to reduce bone loss and nerve side effects in children with leukemia.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly test a new therapy. Results may not lead to immediate changes in care.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Paediatrics and Adolescent Medicine, Aalborg University Hospital

    RECRUITING

    Aalborg, Aalborg, 9000, Denmark

  • Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital

    RECRUITING

    Aarhus N, Aarhus N, 8200, Denmark

  • Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet

    RECRUITING

    Copenhagen, København Ø, 2100, Denmark

  • Department of Paediatrics and Adolescent Medicine, Odense University Hospital

    RECRUITING

    Odense, Odense C, 5000, Denmark

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