University Of Aarhus

This study tests whether a fluorescent dye called indocyanine green (ICG) can help surgeons see and remove all sarcoma tissue during surgery. 90 adults with soft tissue sarcoma in the trunk or limbs will receive the dye before surgery, and the surgeon will use the glow to guide r…

This study looks at whether inducing labor at 39 weeks of pregnancy is better than waiting for labor to start naturally in women with a BMI of 30 or higher. The goal is to see if early induction lowers the chance of needing a C-section. About 1,900 women in Denmark will take part…

This study looks at whether placing a small tube through the chest wall to drain pus from a lung abscess, along with standard antibiotics, helps people recover faster and leave the hospital earlier. About 84 adults with large abscesses will be randomly assigned to get either the …

This study tests whether giving blood transfusions quickly when hemoglobin drops can prevent delirium (sudden confusion) in patients 75 and older after hip fracture surgery. About 198 participants will be randomly assigned to either early transfusion or standard care. Researchers…

This study looks at whether using aspirin alone is as effective and safer than aspirin plus another blood thinner (fondaparinux) before a heart procedure in people with a type of heart attack called NSTEMI. About 5,000 participants will be randomly assigned to one of the two trea…

This study tests whether a procedure to open narrowed kidney arteries (renal artery stenting) helps high-risk patients with resistant high blood pressure, declining kidney function, or heart failure. About 80 participants will either receive the real procedure or a sham procedure…

This study tests whether using a SPECT scan to map healthy, working lung tissue can help doctors aim radiation away from those areas during treatment for advanced lung cancer. The goal is to reduce lung damage and side effects like breathing problems. About 90 people with lung ca…

This registry tracks 160 high-risk patients with resistant hypertension due to narrowed kidney arteries. All patients undergo a procedure called percutaneous transluminal renal angioplasty (balloon dilation, often with a stent) to open the blockage. Researchers will measure chang…

This Danish trial tests whether nurse-led telehealth support helps people with gout stick to their urate-lowering medication and maintain healthy uric acid levels. 200 adults who have already reached target levels will be randomly assigned to either usual care or a support progra…

This study looks at whether DNA markers in urine, vaginal, and cervical samples can better identify endometrial cancer risk in women with postmenopausal bleeding. About 600 participants will provide samples and undergo standard ultrasound. The goal is to see if these non-invasive…

This study aims to see if a special MRI designed for teeth can diagnose jaw joint disorders, tooth infections, and help plan dental implants as well as or better than traditional X-rays. About 470 adults needing dental imaging will get both an MRI and standard X-rays, and the res…

This study is testing whether adding an MRI scan to the usual CT scan helps doctors make better decisions about surgery for pancreatic cancer. About 200 patients who are initially thought to be candidates for surgery will be randomly assigned to get either a standard CT alone or …

This study is testing a new, non-invasive way to detect endometrial cancer using DNA methylation testing on urine and vaginal samples collected by patients themselves. Researchers will compare samples from 120 women—half with endometrial cancer and half healthy—to see if the test…

This study is testing whether offering a liver ultrasound and blood test every 6 months to people with cirrhosis can catch liver cancer early and reduce deaths. About 617 adults aged 40-79 with compensated cirrhosis (no severe complications) in one region of Denmark will be offer…

This study tests whether a therapist-guided exercise program helps people aged 50 and older recover better from a wrist fracture compared to usual care advice. Participants will either receive supervised exercises or standard self-management advice. The main goal is to see if the…

This study looks at whether a combination of two drugs (solifenacin and mirabegron) at low doses works better than a high dose of either drug alone for children aged 5 to 14 with daytime wetting. About 236 children who did not fully respond to low-dose single drugs will be random…

This study tests whether a program of exercise and patient education can reduce hip and groin pain in people with hip dysplasia, compared to usual care. About 200 adults with confirmed hip dysplasia and at least three months of pain will take part. The main goal is to measure pai…

This study tests a new digital follow-up program for people who have had early-stage colorectal cancer. The program uses a smartphone app to monitor symptoms, check for cancer return with a blood test, and provide personalized care. Researchers want to see if it improves quality …

This study tests whether a short form of talk therapy called Focused Acceptance and Commitment Therapy (FACT) can help reduce symptoms of stress, anxiety, and depression. Sixty adults with elevated distress will either receive up to 250 minutes of FACT or be placed on a waitlist.…

This study looks at whether spinal cord stimulation (SCS) actually reduces chronic pain or if it's just a placebo effect. Researchers will compare pain ratings from 25 patients when their SCS device is on, off, or when they are told it's on but it isn't. The goal is to understand…

This study is testing whether a supplement called tributyrin, which the body turns into butyrate, can help lower blood sugar and reduce appetite in people who are overweight or obese. Twelve participants will take either tributyrin or a placebo for two weeks, then switch after a …

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial paralysis after a stroke. About 130 adults with first-time stroke and central facial palsy will be randomly assigned to receive either usual train…

This study looks at whether adding a 12-week progressive resistance training program to a patient education class improves daily function and pain in people with hip osteoarthritis. 150 participants will be randomly assigned to either exercise plus education or education alone, a…

This study tests whether a 12-week progressive resistance exercise program can reduce chronic pain in people with multiple sclerosis. 116 participants will be randomly assigned to either the exercise group or a waitlist control group. The goal is to see if exercise provides a mea…

This study looks at whether combining two common therapy techniques—changing negative thoughts and practicing detached mindfulness—works better than using them alone for people with anxiety or depression. Researchers will compare the effects of each technique and their order. The…

This study tests whether fecal microbiota transplantation (FMT) capsules can help people with diarrhea and colitis caused by immune checkpoint inhibitor cancer treatment. About 20 adults with melanoma or kidney cancer will receive either FMT or placebo capsules alongside their st…

This study tests whether ultrasound scans and patient questionnaires can better track disease activity in people with giant cell arteritis, a condition that inflames arteries and can cause blindness. Researchers will follow 175 patients in remission for one year, using ultrasound…

This study follows 60 kidney transplant recipients in Denmark to find out how often blood vessel problems cause poor kidney function or hard-to-treat high blood pressure. Participants will get special imaging tests, and if a narrowed artery is found, they may receive balloon trea…

This study aims to understand how the information given to patients about their treatment affects their response to migraine medication. Researchers will give 60 adults with chronic migraine four different treatment conditions in a random order and measure changes in headache int…

This study follows 250 people with chronic diverticular disease to see if elective sigmoidectomy (surgery) improves quality of life compared to conservative care (diet, pain relievers, laxatives). Participants are recruited from a surgical clinic in Denmark. The main outcomes are…

This study is testing whether regular patient surveys and a special blood test (circulating tumor DNA) can spot vulva cancer returning earlier than standard check-ups. About 295 women with vulva cancer will fill out symptom surveys every four months and give blood samples for two…

This study looks at how the way treatment information is given affects how well migraine medication works and what side effects people notice. Researchers will give 128 adults with episodic migraine six different treatments in a random order to compare drug effects, placebo effec…

This study watches how hospital staff give breaths during CPR to adults whose hearts stop. It will measure the rate and volume of breaths and see which levels are linked to restarting the heart and surviving 30 days. The goal is to find the best ventilation approach during CPR.

This study tests two common blood-pressure-raising drugs, noradrenaline and phenylephrine, in 32 people undergoing brain tumor surgery. The goal is to see which drug better maintains blood flow and oxygen delivery to the brain and other organs. Researchers will use PET scans to m…

This observational study tracks 500 lung cancer patients receiving a second round of high-dose radiation to the chest. Researchers will collect data on side effects and survival to find safer ways to deliver repeat radiation. The goal is to help doctors personalize treatment and …

This study looks at how different sex hormone levels—like those from natural cycles, hormonal contraception, or medicated IUDs—affect how your muscles and fat respond to regular exercise. Researchers will track 60 women as they do aerobic and resistance training three times a wee…

This study looks at how the steroid dexamethasone, used to treat childhood acute lymphoblastic leukemia, affects bone density and the nervous system. Researchers will measure drug levels in blood and spinal fluid, and track bone loss and nerve-related side effects. The goal is to…

This study will use tiny probes called microdialysis to measure chemicals related to blood flow, inflammation, and antibiotics right inside the amputation stump after surgery. Researchers will compare results between diabetic and non-diabetic patients to understand why some stump…

This study looks at whether a blood test for tumor DNA can better predict if colorectal cancer will come back after surgery. Currently, doctors use tumor tissue to decide who needs chemotherapy, but many patients get chemo they may not need. The test checks for cancer DNA in the …

This observational study will use special PET scans to measure how much oxygen the heart and kidneys use in people with type 1 diabetes. Researchers want to see if a more intensive treatment plan (multifactorial intervention) lowers oxygen demand compared to standard care. Forty …

This study looks at how the hormone glucagon works in people with type 2 diabetes, with or without fatty liver disease. Researchers will give participants low and high doses of glucagon and use scans and blood tests to measure how the liver and heart respond. The goal is to under…

This study tests whether a ketone supplement can improve how the body uses insulin and burns energy. Ten overweight adults aged 55-70 will receive different combinations of growth hormone, a ketone drink, or placebos on separate days. Using advanced PET scans and tissue samples, …

This study aims to understand the sexual health challenges faced by bladder cancer patients and develop a support program tailored to their needs. Researchers will interview 30 patients to learn about their experiences and preferences for professional help. The goal is to create …

This study from Aarhus University is looking at how common magnesium deficiency is in people with Crohn's disease, ulcerative colitis, ileostomy, or bile acid diarrhea. Magnesium is important for muscles, nerves, and heart health, but standard blood tests may miss a deficiency. T…

This study looks at whether experiencing a one-hour time delay every day can shift your body's internal clock. Researchers will measure melatonin levels and reaction times in 40 healthy couples who live together. The goal is to understand how our daily routines affect sleep and c…

This study aims to find out if spinal cord stimulation (SCS) truly reduces pain or if the effect is just due to patients' expectations. Twenty-five adults with chronic pain who already have an SCS implant will take part in four test sessions. During each session, the stimulator w…

This study looks at how being a 'morning person' or 'night owl' changes the way you experience time. Healthy adults aged 23-45 will do computer tasks at their preferred time of day and again at the opposite time. Researchers want to see if time judgments and alertness are worse w…

This study looks at how the body's internal clock changes our perception of time when we stay awake for 36 hours. Thirty healthy adults will remain awake in a controlled lab, with constant light, posture, and food. Every two hours, they complete tests on time estimation, reaction…

This study follows 100 pregnant women with gestational diabetes to understand how their daily blood sugar patterns relate to their baby's growth. Participants wear a continuous glucose monitor for 14 days and have routine checkups. The goal is to learn which blood sugar patterns …

This study watches 250 adults who are unconscious after a cardiac arrest to see if early brain tests can predict when they will wake up. Researchers use tools like EEG and ultrasound to monitor the brain. The goal is to find reliable signs of recovery, not to test a new treatment…

This study uses a special pillbox that records when people with bipolar disorder take their lithium. Over four weeks, 50 participants will use the pillbox and get weekly phone calls to compare what they remember with what the box recorded. The goal is to see how well people stick…

This study looks at whether vaginal estrogen tablets, used to treat vaginal atrophy, change blood clotting factors in postmenopausal women. Researchers will take blood samples before and after 3 months of treatment. The goal is to see if this common treatment might raise or lower…

This study tests whether performing membrane sweeping several times near the due date helps women go into labor on their own before 41 weeks and 3 days. About 1,500 pregnant women with a single baby in head-down position will be randomly assigned to receive either no sweeping or …