New device could make pap smears more comfortable

NCT ID NCT04107181

First seen Mar 10, 2026 · Last updated Jun 23, 2026 · Updated 17 times

Summary

This study tests a new device called the Calla introducer for cervical cancer screening. Researchers want to see if women prefer it over the standard speculum used during Pap smears. About 305 healthy women aged 21-65 will participate. The goal is to improve comfort and screening experience.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Introducer 'Calla' device

What this could lead to

If successful, this could lead to a more comfortable cervical cancer screening experience, potentially increasing screening rates.

What could go wrong

This is a small, early pilot study focused on user preference, not on detecting cancer. The device may not be better than current methods.

Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.