Could a simple urine test replace the pap smear for cervical cancer screening?
NCT ID NCT05413798
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study investigates whether urine samples can be used to screen for cervical cancer in women living with HIV. Researchers will compare the accuracy of urine HPV testing with self-collected and provider-collected samples to detect cervical precancer (CIN2 or worse). The goal is to find a simpler, less invasive screening method that could be used in low-resource settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Urine HPV testing
What this could lead to
If urine HPV testing proves accurate, it could offer a simpler, less invasive way to screen for cervical cancer, especially in low-resource settings.
What could go wrong
This is a validation study, not a treatment trial. The test may not be as accurate as standard methods, and results may not apply to all populations.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clinical HIV Research Unit Temba Lethu Wing Helen Joseph Hospital
RECRUITINGWestdene, Johannesburg, 2092, South Africa
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••