Could a simple urine test replace the pap smear for cervical cancer screening?
NCT ID NCT05413798
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study investigates whether urine samples can be used to screen for cervical cancer in women living with HIV. Researchers will compare the accuracy of urine HPV testing with self-collected and provider-collected samples to detect cervical precancer (CIN2 or worse). The goal is to find a simpler, less invasive screening method that could be used in low-resource settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Urine HPV testing
- What this could lead to
- If urine HPV testing proves accurate, it could offer a simpler, less invasive way to screen for cervical cancer, especially in low-resource settings.
- What could go wrong
- This is a validation study, not a treatment trial. The test may not be as accurate as standard methods, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Clinical HIV Research Unit Temba Lethu Wing Helen Joseph Hospital
RECRUITINGWestdene, Johannesburg, 2092, South Africa
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