New drug combo shows promise for Hard-to-Treat gynecological cancers
NCT ID NCT05512208
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a combination of two drugs, VS-6766 and defactinib, can shrink or control certain gynecological cancers that have come back. It includes women with endometrioid, ovarian, or cervical cancers that have specific gene changes (RAS, BRAF, or NF1). The goal is to see if the treatment is effective and safe, with participants taking the drugs indefinitely as long as they benefit.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AdventHealth
RECRUITINGOrlando, Florida, 32804, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Louisiana State University Medical Center New Orleans
RECRUITINGNew Orleans, Louisiana, 70112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Stephenson Cancer Center
RECRUITINGOklahoma City, Oklahoma, 73117, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of New Mexico Comprehensive Cancer Center
RECRUITINGAlbuquerque, New Mexico, 87131, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••