New drug cocktail shows promise for tough cervical cancer

NCT ID NCT07256236

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase 2 trial is testing a combination of two drugs, Sacituzumab tirumotecan and QL1706, in 89 women with recurrent or metastatic cervical cancer that cannot be treated with surgery or radiation. The goal is to see if the combo can shrink tumors and improve survival. Participants will receive infusions every two weeks until the cancer progresses or side effects become too severe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sacituzumab tirumotecan (SKB264) and QL1706

What this could lead to

If successful, this combination could offer a new treatment option for women with recurrent or metastatic cervical cancer, potentially shrinking tumors or slowing disease progression.

What could go wrong

This is an early-phase, single-arm trial with no placebo group, so results are preliminary. Side effects from the drugs may be significant, and the treatment may not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Jining Medical University

    NOT_YET_RECRUITING

    Jining, Shandong, 272113, China

    Contact

  • Cancer Hospital of Shandong First Medical University

    NOT_YET_RECRUITING

    Jinan, Shandong, 250117, China

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fujian Medical University Affiliated Second Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 362000, China

  • Guangxi Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Nanning, Guangxi, 530213, China

  • Qilu Hospital of Shandong University

    NOT_YET_RECRUITING

    Jinan, Shandong, 250012, China

  • Qilu Hospital of Shandong University(Qingdao)

    NOT_YET_RECRUITING

    Qingdao, Shandong, 266011, China

  • Shandong Provincial Hospital

    NOT_YET_RECRUITING

    Jinan, Shandong, 250013, China

  • Shanxi Cancer Hospital

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 030013, China

  • The Affiliated Hospital of Inner Mongolia Medical University

    NOT_YET_RECRUITING

    Hohhot, Inner Mongolia, 010030, China

  • The Second Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116027, China

  • The Second Qilu Hospital of Shandong University

    NOT_YET_RECRUITING

    Jinan, Shandong, 250012, China

  • Zhangzhou Affiliated Hospital of Fujian Medical University

    RECRUITING

    Zhangzhou, Fujian, 363000, China

    Contact Email: •••••@•••••

  • Zhujiang Hospital of Southern Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510280, China