Could fewer radiation sessions be safer for endometrial cancer?

NCT ID NCT04683653

Recruiting now Symptom relief Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a shorter course of pelvic radiation (called hypofractionation) is safe for women with endometrial cancer. The researchers will find the best dose and see if it reduces bowel and urinary side effects. About 100 women who have already had surgery will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hypofractionated radiation therapy
What this could lead to: If successful, this could offer a shorter, more convenient radiation schedule with fewer side effects for women with endometrial cancer.
What could go wrong: This is an early phase 1/2 study with only 100 participants, so safety and effectiveness are not yet proven. Higher daily radiation doses may increase side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CERVICAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cervical cancer endometrial cancer endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CANCER

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Illinois at Chicago (UIC)
RECRUITING

Chicago, Illinois, 60612, United States
Winship Cancer Institute, Emory University
ACTIVE_NOT_RECRUITING

Atlanta, Georgia, 30322, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.