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Supercharged immune cells take on HPV cancers

NCT ID NCT05686226

Recruiting now Disease control Sponsor: Christian Hinrichs Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new immunotherapy for people with advanced HPV-related cancers, such as cervical, throat, anal, and penile cancers. Participants receive specially engineered immune cells designed to attack cancer cells carrying the HPV16 virus. The goal is to see if this treatment can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal carcinoma anal squamous cell carcinoma anus neoplasm cervical adenocarcinoma cervical cancer endocervical adenocarcinoma human papillomavirus-related penile squamous cell carcinoma human papillomavirus-related squamous cell carcinoma metastatic malignant neoplasm Neoplasm Metastasis oropharynx cancer oropharynx squamous cell carcinoma penile cancer penile neoplasm squamous cell carcinoma of rectum Uterine Cervical Neoplasms vaginal adenocarcinoma vaginal cancer vulva cancer vulvar squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAL CANCER CERVICAL CANCER HPV POSITIVE OROPHARYNGEAL SQUAMOUS CELL CARCINOMA HPV POSITIVE RECTAL SQUAMOUS CELL CARCINOMA HPV-ASSOCIATED VAGINAL ADENOCARCINOMA HPV-RELATED ADENOCARCINOMA HPV-RELATED ADENOSQUAMOUS CARCINOMA HPV-RELATED ANAL SQUAMOUS CELL CARCINOMA HPV-RELATED CARCINOMA HPV-RELATED CERVICAL CARCINOMA HPV-RELATED ENDOCERVICAL ADENOCARCINOMA HPV-RELATED MALIGNANCY HPV-RELATED PENILE SQUAMOUS CELL CARCINOMA HPV-RELATED SQUAMOUS CELL CARCINOMA HPV-RELATED VULVAR SQUAMOUS CELL CARCINOMA METASTATIC CANCER OROPHARYNX CANCER PENILE CANCER THROAT CANCER VAGINAL CANCER VULVA CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • RWJBarnabas Health - Robert Wood Johnson University Hospital

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rutgers Cancer Institute

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••