HPV-RELATED MALIGNANCY
Clinical trials for HPV-RELATED MALIGNANCY explained in plain language.
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Supercharged immune cells take on HPV cancers
Disease control Recruiting nowThis study tests a new immunotherapy for people with advanced HPV-related cancers (cervical, throat, anal, and others). Participants receive specially engineered immune cells designed to attack HPV-infected tumor cells, along with chemotherapy and a drug to boost cell activity. T…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 17, 2026 02:58 UTC
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New combo aims to revive immune attack on hard-to-treat cervical cancer
Disease control Recruiting nowThis study tests a new drug, PRGN-2009, combined with pembrolizumab in 24 adults whose recurrent or metastatic cervical cancer no longer responds to pembrolizumab alone. The goal is to see if the combination can shrink tumors or stop them from growing. Participants must have HPV-…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Precigen, Inc • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Immune cells take aim at HPV tumors before standard therapy
Disease control Recruiting nowThis study tests whether giving a single dose of specially engineered immune cells (E7 TCR-T cells) before standard treatment (chemoradiation or surgery) can shrink or eliminate tumors in people with advanced HPV-related cancers. About 15 participants will have their own T cells …
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE1, PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Blood test may spare some throat cancer patients from unnecessary radiation
Disease control Recruiting nowThis study is for people with HPV-related throat cancer who have had or will have surgery. Researchers will use a blood test that looks for cancer DNA (HPV ctDNA) to decide if radiation therapy is needed. In one group, patients with no detectable cancer DNA after surgery will ski…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 24, 2026 16:17 UTC