New targeted drug shows promise for Hard-to-Treat cancers

NCT ID NCT06465069

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 24 times

Summary

This study tests a new drug called LY4052031 in people with advanced or metastatic solid tumors, including bladder, breast, lung, and other cancers. The drug is designed to target and attack cancer cells while sparing healthy ones. The trial has two parts: first to find the safest dose, then to see how well it shrinks tumors. About 420 participants will take part, and the study will last up to 4 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aichi Cancer Center Hospital

    RECRUITING

    Nagoya, 464-8681, Japan

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Beijing Cancer hospital

    RECRUITING

    Beijing, 100142, China

  • Catalan Institute of Oncology Duran i Reynals Hospital

    RECRUITING

    Barcelona, 8908, Spain

  • City of Hope National Medical Center

    RECRUITING

    Duarte, California, 91010-0269, United States

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032-3729, United States

  • Florida Cancer Specialists and Research Institute

    RECRUITING

    St. Petersburg, Florida, 33705, United States

  • Hospital Madrid Norte Sanchinarro

    RECRUITING

    Madrid, 28050, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Virgen Del Rocio

    RECRUITING

    Seville, 41013, Spain

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029-6574, United States

  • Institut Gustave Roussy (Igr)

    RECRUITING

    Villejuif, 94805, France

  • Linear Clinical Research

    RECRUITING

    Nedlands, 6009, Australia

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa, Chiba, 277-8577, Japan

  • Renji Hospital, Shanghai Jiaotong University School of Medicine

    NOT_YET_RECRUITING

    Shanghai, 200000, China

  • START Midwest Cancer and Hematology Centers of W Michigan

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at HealthOne

    RECRUITING

    Denver, Colorado, 80218, United States

  • South Texas Accelerated Research Therapeutics (START)

    RECRUITING

    San Antonio, Texas, 78229, United States

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1A 7BE, United Kingdom

  • St Vincent's Hospital

    RECRUITING

    Darlinghurst, 2010, Australia

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, 510060, China

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Kōtō City, 135-8550, Japan

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • University of Chicago Hospital

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030-4000, United States

  • University of Utah - Huntsman Cancer Institute

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Washington University School of Medicine in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.