New iron injection shows promise in shrinking tumors

NCT ID NCT07433283

Recruiting now Disease control Sponsor: Sichuan Enray Pharmaceutical Sciences Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called CNSI-Fe(II), which is injected directly into tumors. It uses iron to trigger a type of cell death called ferroptosis, aiming to control advanced solid tumors like lung, pancreas, and colorectal cancers. The trial involves 54 adults whose current treatments have stopped working. The goal is to check safety and see if the drug can shrink or stabilize tumors.

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Conditions

The condition(s) this trial relates to.

cervical cancer colorectal cancer colorectal neoplasm lung cancer lung neoplasm malignant pancreatic neoplasm neoplasm pancreatic neoplasm thyroid cancer Thyroid Neoplasms Uterine Cervical Neoplasms vulva cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER COLORECTAL CANCER LUNG CANCER PANCREAS CANCER THYROID CANCER TUMOR, SOLID VULVA CANCER

Contacts and locations

Locations

Fudan University Shanghai Cancer Center
NOT_YET_RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Fujian provincial cancer hospital
NOT_YET_RECRUITING

Fuzhou, Fujian, 350014, China
Harbin medical university cancer hospital
NOT_YET_RECRUITING

Heilongjiang, Harbin, 150081, China
Hunan Provincial Tumor Hospital
NOT_YET_RECRUITING

Hunan, Changsha, 410000, China
Peking Union Medical College Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100005, China
Second Affiliated Hospital of Hainan Medical University
RECRUITING

Haikou, Hainan, 571626, China
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 400042, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Henan, Zhengzhou, 450052, China
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China

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