Virus therapy takes on cervical and endometrial cancer
NCT ID NCT06552598
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a modified virus (KD01) that targets and kills cancer cells, given alone or with an immunotherapy drug (AK104). It includes 97 women with cervical or endometrial cancer, some of whom have not responded to standard treatments. The goal is to see if the virus is safe and can shrink tumors, especially in younger women who want to preserve fertility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- KD01 (a modified virus that targets and kills cancer cells) combined with AK104 (an immunotherapy drug) and other agents
- What this could lead to
- If successful, this could offer a new treatment option for gynecologic cancers, potentially preserving fertility in younger women.
- What could go wrong
- This is an early Phase I/II trial with a small number of participants, so safety and effectiveness are not yet proven. The virus and immunotherapy may cause side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430030, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an antiviral make radiation more effective against cervical cancer?
- What raises endometrial cancer risk in black women? a study digs in
- Can adding radiation boost the power of immunotherapy in advanced cervical cancer?
- A One-Two punch against cervical cancer: testing plus vaccination in HIV-Positive women
- Can a Two-Antibody combo outsmart advanced cancer?