Robot or scalpel? a Head-to-Head trial for cervical cancer surgery

NCT ID NCT04831580

Recruiting now Disease control Sponsor: GOG Foundation Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial compares two surgical approaches for early-stage cervical cancer: robotic-assisted surgery using the da Vinci system versus traditional open surgery. Researchers are asking whether the minimally invasive robotic method can match or improve upon open surgery in terms of cancer-free survival three years after treatment. The study enrolls 840 women with specific early-stage cervical cancer types and stages, aiming to clarify the best surgical option for long-term outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: robotic-assisted surgery using the da Vinci system
What this could lead to: If robotic surgery proves as effective as open surgery, it could offer a less invasive option with faster recovery for early-stage cervical cancer patients.
What could go wrong: This is a large trial, but robotic surgery may still carry higher risks of certain complications or lower survival rates compared to the traditional open approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER

Contacts and locations

Locations

A.C.Camargo Cancer Center
RECRUITING

São Paulo, São Paulo, 01509001, Brazil
AHN West Penn Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15224, United States
Abington Memorial Hospital
RECRUITING

Abington, Pennsylvania, 19001, United States
Alliance Cancer Specialists, PC
RECRUITING

Wynnewood, Pennsylvania, 19096, United States
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Ascension Medical Group St. Vincent's Obstetrics and Gynecology
RECRUITING

Jacksonville, Florida, 32204, United States
Asplundh Cancer Pavillion
RECRUITING

Willow Grove, Pennsylvania, 19090, United States
Baptist Health
RECRUITING

Lexington, Kentucky, 40503, United States
Baptist Health Lexington
RECRUITING

Lexington, Kentucky, 40503, United States
Barretos Cancer Hospital
RECRUITING

Barretos, São Paulo, 14784-400, Brazil
Baystate Medical Center
WITHDRAWN

Springfield, Massachusetts, 01199, United States
Brazilian National Cancer Institute
RECRUITING

Rio de Janeiro, 20081-250, Brazil
CHA Bundang Medical Center
RECRUITING

Seongnam-si, Gyeonggi-do, 13496, South Korea
California Pacific Medical Center-Research Institute
WITHDRAWN

San Francisco, California, 91409, United States
Center of Hope
RECRUITING

Reno, Nevada, 89511, United States
Centre Hospitalier De L'Universite De Montreal
RECRUITING

Montreal, H2X 3E4, Canada
Chattanooga's Program in Women's Oncology
RECRUITING

Chattanooga, Tennessee, 37403, United States
City of Hope
RECRUITING

Duarte, California, 91010, United States
City of Hope - Upland
RECRUITING

Upland, California, 91786, United States
City of Hope Orange County Lennar Foundation Cancer
RECRUITING

Irvine, California, 92618, United States
David C. Pratt Center
RECRUITING

St Louis, Missouri, 63141, United States
Duke Cancer Center
RECRUITING

Durham, North Carolina, 27710, United States
Duke Cancer Center
RECRUITING

Durham, North Carolina, 27710, United States
Duke University Hospital
RECRUITING

Durham, North Carolina, 27705, United States
FirstHealth Outpatient Cancer Center
WITHDRAWN

Pinehurst, North Carolina, 28374, United States
Gangnam Severance Hospital
RECRUITING

Seoul, Republic of Korea, 06273, South Korea
Georgian Cancer Center at Augusta University
RECRUITING

Augusta, Georgia, 30912, United States
Harford HealthCare Cancer Institute at the Hospital of Central Connecticut
RECRUITING

New Britain, Connecticut, 06053, United States
Hartford Healthcare Cancer Institute at Hartford Hospital
RECRUITING

Hartford, Connecticut, 06106, United States
Hartford Healthcare Medical Group-Manchester
RECRUITING

Manchester, Connecticut, 06042, United States
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States
Hoag Gynecologic Oncology
RECRUITING

Newport Beach, California, 92633, United States
Hoag Memorial Hospital Presbyterian
RECRUITING

Newport Beach, California, 92663, United States
Hospital Erasto Gaertner
RECRUITING

Curitiba, Paraná, 81520-060, Brazil
Hospital Municipal Vila Santa Catarina
RECRUITING

São Paulo, Sao Paula, 04378-500, Brazil
Hospital de Base - Fundacao Faculdade Regional de Medicina de São José do Rio Preto
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Inova Health System
RECRUITING

Fairfax, Virginia, 22031, United States
James Cancer Hospital & Solove Research Institute at The Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States
JamesCare Gynecologic Oncology at Mill Run
RECRUITING

Hilliard, Ohio, 43026, United States
Josie Robertson Surgery Center
RECRUITING

New York, New York, 10065, United States
Kettering Health Cancer Center
RECRUITING

Kettering, Ohio, 45429, United States
Korea University Anam Hospital
RECRUITING

Seoul, 02843, South Korea
Korea University Guro Hospital
RECRUITING

Seoul, Republic of Korea, 08308, South Korea
LSU Health New Orleans
RECRUITING

New Orleans, Louisiana, 70112, United States
Laura and Issac Perlmutter Cancer Center at NYU Langone
RECRUITING

Brooklyn, New York, 11220, United States
Laura and Issac Perlmutter Cancer Center at NYU Langone
RECRUITING

New York, New York, 10016, United States
Laura and Issac Perlmutter Cancer Center at NYU Langone-East 34th Street
RECRUITING

New York, New York, 10016, United States
Legacy Good Samaritan Medical Center-Gynecological Oncology Group
WITHDRAWN

Portland, Oregon, 97210, United States
Legacy Meridian Park Medical Center-Legacy Medical Gynecologic Oncology
WITHDRAWN

Tualatin, Oregon, 97062, United States
Legacy Salmon Creek Medical Center-Legacy Medical Group Gynecologic Oncology
WITHDRAWN

Vancouver, Washington, 98686, United States
M Health Fairview University of Minnesota Medical Center-East Bank Hospital
RECRUITING

Minneapolis, Minnesota, 55455, United States
M Health Fairview University of Minnesota Medical Center-East Bank Hospital
RECRUITING

Minneapolis, Minnesota, 55455, United States
Magee - Womens Hospital of UPMC
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Maine Medical Partners-Woman's Health-Division of Gynecologic Oncology
RECRUITING

Scarborough, Maine, 04074, United States
McGill University Health Centre-Glen Site
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
Memorial Sloan Kettering (Basking Ridge)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering (Bergen)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering (Commack)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering (Monmouth)
RECRUITING

Middletown, New York, 07748, United States
Memorial Sloan Kettering (Nassau)
RECRUITING

Uniondale, New York, 11553, United States
Memorial Sloan Kettering (Westchester)
RECRUITING

Harrison, New York, 10604, United States
Memorial Sloan Kettering Cancer Center (Main Campus)
RECRUITING

New York, New York, 10065, United States
Mercy Hospital
RECRUITING

Miami, Florida, 33133, United States
Mercy Hospital
RECRUITING

Miami, Florida, 33173, United States
Miami Cancer Institute at Baptist Health, Inc.
RECRUITING

Miami, Florida, 33176, United States
Miami Cancer Institute at Baptist Health, Inc.
RECRUITING

Miami, Florida, 33176, United States
Minnesota Oncology Hematology
RECRUITING

Minneapolis, Minnesota, 55404, United States
Mount Sinai Comprehensive Cancer Center
WITHDRAWN

Miami, Florida, 33140, United States
NHPP/Gynecologic Oncology at New Hyde Park
RECRUITING

New Hyde Park, New York, 11042, United States
NYU Langone Ambulatory Care Bay Ridge
RECRUITING

Brooklyn, New York, 11220, United States
NYU Langone Hospital-Brooklym
RECRUITING

Brooklyn, New York, 11220, United States
NYU Langone Medical Center (Tisch Hospital)
RECRUITING

New York, New York, 10016, United States
Northwell Health Physician Partners/Gynecological Oncology at Brightwaters
RECRUITING

Brightwaters, New York, 11718, United States
Northwell Health/Huntington Hospital
RECRUITING

Huntington, New York, 11743, United States
Northwell Health/Long Island Jewish Medical Center
RECRUITING

New Hyde Park, New York, 11040, United States
Northwell Health/South Shore University Hospital
RECRUITING

Bay Shore, New York, 11706, United States
Novant Health Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Novant Health Cancer Institute
RECRUITING

Greensboro, North Carolina, 27403, United States
Novant Health Cancer Institute
RECRUITING

Kernersville, North Carolina, 27284, United States
Novant Health Cancer Institute
RECRUITING

Mount Airy, North Carolina, 27030, United States
Novant Health Cancer Institute
RECRUITING

North Wilkesboro, North Carolina, 28659, United States
Novant Health Cancer Institute
RECRUITING

Statesville, North Carolina, 28625, United States
Novant Health Cancer Institute
RECRUITING

Thomasville, North Carolina, 27360, United States
Novant Health Cancer Institute
RECRUITING

Winston-Salem, North Carolina, 27103, United States
OSU Wexner Medical Center Hospital East
RECRUITING

Columbus, Ohio, 43203, United States
OSU Wexner Medical Center Martha Morehouse Outpatient Care
RECRUITING

Columbus, Ohio, 43221, United States
OSU Wexner Medical Center Outpatient Care Dublin
RECRUITING

Dublin, Ohio, 43016, United States
OSU Wexner Medical Center Outpatient Care East
RECRUITING

Columbus, Ohio, 43203, United States
OSU Wexner Medical Center Outpatient Care Gahanna
RECRUITING

Columbus, Ohio, 43230, United States
OSU Wexner Medical Center Outpatient Care Lewis Center
RECRUITING

Lewis Center, Ohio, 43035, United States
OSU Wexner Medical Center Outpatient Care New Albany
RECRUITING

Westerville, Ohio, 43081, United States
OSU Wexner Medical Center Outpatient Care Upper Arlington
RECRUITING

Columbus, Ohio, 43221, United States
OSU Wexner Medical Center Stefanie Spielman Comprehensive Breast Center
RECRUITING

Columbus, Ohio, 43212, United States
OSU Wexner Medical Center University Hospital
RECRUITING

Columbus, Ohio, 43210, United States
Orlando Health Cancer Center
WITHDRAWN

Orlando, Florida, 32806, United States
Orlando Health Winnie Palmer Hospital for Woman and Babies
WITHDRAWN

Orlando, Florida, 32806, United States
Palo Alto Medical Foundation
WITHDRAWN

Palo Alto, California, 94040, United States
Princess Margaret Cancer Center
RECRUITING

Toronto, Ontario, M5G2M9, Canada
Providence Center Institute Franz Clinic
RECRUITING

Portland, Oregon, 97213, United States
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul St. Mary's Hospital - Catholic University
RECRUITING

Seoul, 06591, South Korea
Severance Hospital - Yonsei Cancer Center
RECRUITING

Seoul, Republic of Korea, 07722, South Korea
Severance Hospital - Yonsei Cancer Center
RECRUITING

Seoul, 07722, South Korea
South Miami Hospital
RECRUITING

Miami, Florida, 33143, United States
South Miami Hospital
RECRUITING

Miami, Florida, 33143, United States
Southeastern Regional Medical Center LLC
WITHDRAWN

Newnan, Georgia, 30265, United States
St. Elizabeth Healthcare
ACTIVE_NOT_RECRUITING

Edgewood, Kentucky, 41017, United States
St. Vincent Hospital and Health Care Center Inc
WITHDRAWN

Indianapolis, Indiana, 46260, United States
St. Vincent Hospital and Health Care Center, Inc
WITHDRAWN

Indianapolis, Indiana, 46260, United States
Stanford Hospital
RECRUITING

Palo Alto, California, 94305, United States
Stephenson Cancer Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Summa Health Jean and Milton Copper Pavilion
RECRUITING

Akron, Ohio, 44304, United States
Summa Health Jean and Milton Copper Pavillion
RECRUITING

Akron, Ohio, 44304, United States
Tampa General Hospital
WITHDRAWN

Tampa, Florida, 33606, United States
Texas Oncology
RECRUITING

Fort Worth, Texas, 76104, United States
Texas Oncology- Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology- GYN ONC DFWW
RECRUITING

Bedford, Texas, 76022, United States
Texas Oncology-Austin
RECRUITING

Austin, Texas, 78758, United States
Texas Oncology-DFWW
RECRUITING

Bedford, Texas, 76022, United States
Texas Oncology-GYN ONC DFWW
RECRUITING

Fort Worth, Texas, 76104, United States
Texas Oncology-San Antonio
RECRUITING

San Antonio, Texas, 78240, United States
Texas Oncology-The Woodlands, Gynecologic Oncology
RECRUITING

The Woodlands, Texas, 77380, United States
The Blavatnik Family - Chelsea Medical Center at Mount Sinai
RECRUITING

New York, New York, 10029, United States
The West Clinic, PLLC dba West Cancer Center
RECRUITING

Germantown, Tennessee, 38119, United States
TriHealth Cancer Institute-Good Samaritan Hospital
ACTIVE_NOT_RECRUITING

Cincinnati, Ohio, 45220, United States
TriHealth Cancer Institute-Thomas Comprehensive Care Center
ACTIVE_NOT_RECRUITING

Cincinnati, Ohio, 45220, United States
UCLA Gynecologic Oncology Clinic
RECRUITING

Los Angeles, California, 90095, United States
University of California San Diego Medical Center
RECRUITING

Encinitas, California, 92024, United States
University of California San Diego Medical Center
RECRUITING

La Jolla, California, 92037, United States
University of California San Diego Medical Center
RECRUITING

San Diego, California, 92103, United States
University of California San Diego Medical Center
RECRUITING

Vista, California, 92081, United States
University of California San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of New Mexico Comprehensive Cancer Center
ACTIVE_NOT_RECRUITING

Albuquerque, New Mexico, 87131, United States
University of Pennsylvania Health System, Perelman Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Medical Center-Simmons Cancer Center
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Medical Center-WIlliam P. Clements Jr. University Hospital
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Medical Center-Zale Lipshy University Hospital
RECRUITING

Dallas, Texas, 75390, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22903, United States
University of Virginia Comprehensive Cancer Center
RECRUITING

Charlottesville, Virginia, 22903, United States
University of Wisconsin Clinical Science Center
RECRUITING

Madison, Wisconsin, 53792, United States
VCU Health Emergency Center at New Kent
RECRUITING

Quinton, Virginia, 23141, United States
VCU Health Short Pump Pavillion
RECRUITING

Richmond, Virginia, 23233, United States
VCU Health at GreenGate
RECRUITING

Henrico, Virginia, 23233, United States
VCU Health at Tappahannock Hospital
ACTIVE_NOT_RECRUITING

Tappahannock, Virginia, 25560, United States
VCU Health-William and Mary
RECRUITING

Williamsburg, Virginia, 23185, United States
VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States
Virginia Commonwealth University Massey Cancer Center
RECRUITING

Richmond, Virginia, 23219, United States
Virginia Commonwealth University-Main Hospital
RECRUITING

Richmond, Virginia, 23298, United States
West Virginia
RECRUITING

Morgantown, West Virginia, 26506, United States
West Virginia University
RECRUITING

Morgantown, West Virginia, 26506, United States
Western Regional Medical Center LLC
WITHDRAWN

Goodyear, Arizona, 85338, United States
Willis-Knighton Physician Network Gynecologic Oncology Associates
RECRUITING

Shreveport, Louisiana, 71118, United States
Women's and Infants Hospital of Rhode Island Program in Women's Oncology
RECRUITING

Providence, Rhode Island, 02905, United States

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