New targeted therapy TER-2013 enters trials for Hard-to-Treat cancers

NCT ID NCT07109726

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This study tests an experimental drug called TER-2013 in people with advanced solid tumors (like breast, endometrial, ovarian, lung, head and neck, esophageal, or cervical cancer) that have specific genetic changes in the AKT/PI3K/PTEN pathway. The trial has two phases: first, finding a safe dose, and second, seeing how well the drug shrinks tumors. About 205 participants will receive the drug, and researchers will monitor side effects, drug levels in the body, and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Carolina BioOncology Institute

    RECRUITING

    Huntersville, North Carolina, 28078, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Florida Cancer Specialists - Lake Nona

    RECRUITING

    Orlando, Florida, 32827, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Froedtert & MCW Cancer Center

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02144, United States

  • Mayo Rochester

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    Austin, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NEXT Oncology

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68130, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • PanOncology Trials

    RECRUITING

    San Juan, 00935, Puerto Rico

    Contact Email: •••••@•••••

  • START Center for Cancer Research

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Center for Cancer Research

    RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarah Cannon Nashville

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UH Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-••••

  • Washington Univ. School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.