Gut bacteria may hold key to better cancer therapy

NCT ID NCT07263620

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study investigates whether the unique bacteria found inside digestive system tumors can help predict how well a patient will respond to neoadjuvant therapy (chemotherapy before surgery). Researchers will analyze tumor samples from 90 adults with pancreatic, gastric, colorectal, or esophageal cancer. The goal is to develop a model that identifies which patients are most likely to benefit from this treatment, potentially improving outcomes and reducing unnecessary side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a test that helps doctors choose which patients will benefit from neoadjuvant therapy for digestive cancers.
What could go wrong
This is an early exploratory study with only 90 participants, so results may not apply to all patients. The findings are observational and need further validation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Patients with esophageal, pancreatic, gastric, or colorectal cancer who are scheduled to receive neoadjuvant therapy

    RECRUITING

    Tianjin, China

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