New pill aims to keep pancreatic cancer away after surgery

NCT ID NCT07252232

Recruiting now Disease control Sponsor: Revolution Medicines, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tests a new drug called daraxonrasib in people with pancreatic cancer who have already had surgery and chemotherapy. The goal is to see if taking the drug can delay or prevent the cancer from returning compared to just watching and waiting. About 500 adults will be randomly assigned to receive the drug or no additional treatment.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER PDAC PDAC - PANCREATIC DUCTAL ADENOCARCINOMA RESECTABLE PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) RESECTED PANCREATIC ADENOCARCINOMA

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Avera Cancer Institute
RECRUITING

Sioux Falls, South Dakota, 57105, United States
Azienda Ospedaliero Universitaria Pisana
RECRUITING

Pisa, 56126, Italy
Beatson West of Scotland Cancer Centre
RECRUITING

Glasgow, G22 0YN, United Kingdom
CRLCC Eugene Marquis
RECRUITING

Rennes, Cedex, 35042, France
Cancer Institute Hospital of JFCR
RECRUITING

Tokyo, 135-8550, Japan
Cedars-Sinai Cancer at Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centro Ricerche Cliniche di Verona s.r.l.
RECRUITING

Verona, 37134, Italy
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States

Contact Email: •••••@•••••
Community Health Network
RECRUITING

Indianapolis, Indiana, 46250, United States
Comprehensive Cancer Centers of Nevada
RECRUITING

Las Vegas, Nevada, 89169, United States
Dana Farber Cancer Institute (DFCI)
RECRUITING

Boston, Massachusetts, 02215, United States
Dong-A University Hospital
RECRUITING

Busan, 49201, South Korea
Duke Cancer Center
RECRUITING

Durham, North Carolina, 27710, United States
Florida Cancer Specialists
RECRUITING

St. Petersburg, Florida, 33701, United States
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
Hartford Healthcare
RECRUITING

Hartford, Connecticut, 06103, United States
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Universitari Vall d'Hebron - VHIO
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain
Hôpital Paul Brousse
RECRUITING

Villejuif, Val-De- Marne, 94804, France
IEO - Instituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy
IOV - Istituto Oncologico Veneto IRCCS
RECRUITING

Padova, 35128, Italy
Imperial College Healthcare NHS Foundation Trust, Hammersmith Hospital
RECRUITING

London, W12 0HS, United Kingdom
Institut Gustave Roussy
RECRUITING

Villejuif, Val-de-Marne, 94805, France
Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Kyoto University Hospital
RECRUITING

Kyoto, 606-8507, Japan
Laura and Issac Perlmutter Cancer Center at NYU Langone-Ambulatory Care Center
RECRUITING

New York, New York, 10016, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Mayo Clinic
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic Cancer Center
RECRUITING

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
National Cancer Center Hospital East
RECRUITING

Chiba, 277-8577, Japan
Pan American Oncology Trials, LLC
RECRUITING

San Juan, 00909, Puerto Rico

Contact Email: •••••@•••••
Rocky Mountain Cancer Centers, LLP
RECRUITING

Lakewood, Colorado, 80228, United States
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
Saint Luke's Cancer Institute
RECRUITING

Kansas City, Missouri, 64111, United States
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins & Sibley Memorial Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
Stanford Cancer Institute
RECRUITING

Palo Alto, California, 94304, United States
Taylor Cancer Research Center
RECRUITING

Maumee, Ohio, 43537, United States
Texas Oncology - DFW
RECRUITING

Dallas, Texas, 75246, United States
Texas Oncology - Northeast Texas
RECRUITING

Longview, Texas, 75601, United States
The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The Royal Marsden NHS Foundation Trust, Royal Marsden Hospital-London
RECRUITING

London, SW3 6JJ, United Kingdom

Contact Email: •••••@•••••
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92037, United States
Universitaetsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany
University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Medical Centre
RECRUITING

Birmingham, B15 2TH, United Kingdom
University of California, Los Angeles
RECRUITING

Los Angeles, California, 90404, United States
University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Kansas Medical Center Research Institute, Inc.
RECRUITING

Lawrence, Kansas, 66045, United States
University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center
RECRUITING

Miami, Florida, 33136, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Texas MD Anderson Cancer Center
NOT_YET_RECRUITING

Houston, Texas, 77030, United States

Contact Email: •••••@•••••
University of Utah, Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 94112, United States
Virginia Cancer Specialists
RECRUITING

Fairfax, Virginia, 22031, United States
Winship Cancer Institute, Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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