PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Clinical trials for PDAC - PANCREATIC DUCTAL ADENOCARCINOMA explained in plain language.
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Experimental cancer drug enters first human trials for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in humans testing a new cancer drug called AVA6103. The trial aims to find a safe dose and see if the drug shows early signs of helping patients with advanced solid tumors that have spread or cannot be removed by surgery. It will enroll adults with specifi…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Avacta Life Sciences Ltd • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New drug targets multiple KRAS mutations in advanced cancers
Disease control Recruiting nowThis early-stage trial is testing a new drug called BBO-11818 in people with advanced cancers that have specific KRAS gene mutations. The study aims to find a safe dose and see if the drug can shrink tumors in cancers like lung, pancreatic, and colorectal cancer. Participants wil…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New drug combo targets tough cancers in groundbreaking trial
Disease control Recruiting nowThis study is testing whether a new oral drug called TNG462 is safe and effective when combined with other cancer drugs for people with advanced pancreatic or non-small cell lung cancer. The trial will involve about 183 adults whose cancers have specific genetic changes (MTAP los…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for pancreatic cancer patients in global drug trial
Disease control Recruiting nowThis study is testing whether a new drug called daraxonrasib, given alone or with standard chemotherapy, works better than chemotherapy alone for people with advanced pancreatic cancer that has spread. About 900 participants will be randomly assigned to receive one of three treat…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Tiny 'Dream Vectors' target deadly pancreatic tumors in new trial
Disease control Recruiting nowThis study is testing whether adding a new experimental treatment to standard chemotherapy helps people with advanced pancreatic cancer that has worsened after initial therapy. The experimental treatment uses tiny 'nanocells' designed to deliver chemotherapy directly to cancer ce…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Engeneic Pty Limited • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Three-Pronged attack aims to stop dangerous leaks after major cancer surgery
Disease control Recruiting nowThis international study is testing whether a combination of three existing treatments can reduce serious complications after a complex surgery to remove pancreatic tumors. The surgery, called a pancreatoduodenectomy, has a high risk of a dangerous fluid leak. The trial will enro…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE4 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New hope for tough cancers: first patients test novel drug
Disease control Recruiting nowThis is a first-in-human study to test the safety and find the right dose of a new drug called TJ033721 (givastomig) for people with advanced or metastatic solid tumors. It will enroll about 330 patients whose cancer has progressed despite standard treatments or who have no other…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: I-Mab Biopharma US Limited • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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New pill targets common cancer driver in advanced tumors
Disease control Recruiting nowThis early-stage trial is testing a new oral medication called ALTA3263 in adults with advanced solid tumors that have specific KRAS mutations. The study aims to find a safe dose and see how the body processes the drug, while also checking for early signs that it might help contr…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Alterome Therapeutics, Inc. • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New hope to keep pancreatic cancer from returning after surgery
Disease control Recruiting nowThis study is testing whether a new oral drug, daraxonrasib, can help keep pancreatic cancer from coming back after surgery and chemotherapy. It will compare the drug to standard observation (no drug) in 500 patients who have had their tumor surgically removed and completed chemo…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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Could controlling blood sugar help fight pancreatic cancer?
Disease control Recruiting nowThis study is testing whether closely monitoring and managing blood sugar levels might help people with pancreatic cancer respond better to chemotherapy. About 50 participants will use continuous glucose monitors while receiving standard chemotherapy. Half will aim for tight bloo…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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Could a simple breath test spot deadly pancreatic cancer sooner?
Diagnosis Recruiting nowThis study is developing a simple breath test to help detect pancreatic cancer earlier. It will involve about 1,000 people, including those with pancreatic cancer, other pancreatic conditions, and general stomach issues. Researchers will analyze tiny molecules in breath to see if…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Diagnosis
Last updated Mar 19, 2026 14:55 UTC
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Could a simple breath test spot deadly cancer sooner?
Diagnosis Recruiting nowThis study is testing a new, non-invasive breath test designed to help detect pancreatic cancer earlier. It will involve over 6,000 adults who have been referred by their doctor for possible pancreatic cancer due to vague symptoms. The goal is to see if the test can accurately id…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Diagnosis
Last updated Mar 18, 2026 14:42 UTC
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Massive 5,000-Person hunt for pancreatic Cancer's early warning signs
Knowledge-focused Recruiting nowThis study is creating a large registry of people at high risk for pancreatic cancer to help researchers find better ways to detect the disease early. It will collect blood samples, pancreatic fluid, and medical images from 5,000 participants over ten years. The goal is to use th…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC