Blood sugar control may boost chemo in pancreatic cancer

NCT ID NCT05132244

Recruiting now Disease control Sponsor: British Columbia Cancer Agency Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study looks at whether closely monitoring and managing blood sugar levels can help people with pancreatic cancer. About 50 participants will wear a continuous glucose monitor during chemotherapy. Half will get intensive glucose management from an endocrinologist, while the other half gets standard care. The goal is to see if tight glucose control is feasible and might improve cancer outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: standard anti-hyperglycemic drugs (metformin, insulin, GLP-1 agonists, SGLT2 inhibitors, DPP-4 inhibitors)
What this could lead to: If it works, this could show that tight glucose control improves how well chemotherapy works for pancreatic cancer.
What could go wrong: This is a small pilot study with only 50 people, so results may not apply to everyone. It is testing feasibility, not yet proving benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hyperglycemia malignant pancreatic neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERGLYCEMIA PANCREATIC CANCER PDAC - PANCREATIC DUCTAL ADENOCARCINOMA

Contacts and locations

Locations

British Columbia Cancer
RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada

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