British Columbia Cancer Agency

This study tests the drug atezolizumab in about 200 adults with different incurable solid tumors. Researchers use each person's tumor DNA and RNA to see if their cancer might respond to the drug. Participants receive the same dose every 3 weeks, and the study checks if the geneti…

This study tests if giving radiation in just 2 sessions works as well as the standard 5 sessions for men with intermediate-risk prostate cancer. The goal is to see if fewer treatments cause fewer side effects and are more convenient, while still controlling the cancer. All partic…

This early-phase trial tests a new treatment called CLIC-2201 for people with B-cell blood cancers that have come back or not responded to standard therapy. CLIC-2201 is made from a patient's own immune cells, which are modified in a lab to better recognize and attack cancer cell…

This study looks at whether closely monitoring and controlling blood sugar levels can help people with pancreatic cancer who are receiving chemotherapy. About 50 participants will wear a continuous glucose monitor and be randomly assigned to either tight blood sugar control or st…

This study tests whether a precise, high-dose radiation treatment (SABR) works better than standard palliative radiation for people with cancer that has spread to a few spots and is starting to grow again. About 194 adults with solid tumors (not lymphoma or myeloma) and up to 5 g…

This study tests if shorter, more intense radiation (SABR or brachytherapy) is as safe and works as well as standard radiation for men with prostate cancer that has spread to a few other spots. About 168 participants will receive one of the treatments. The goal is to find a more …

This study tests a precise, high-dose radiation treatment (brachytherapy) for men whose prostate cancer has returned after previous radiation. About 30 participants will receive this salvage therapy to control the cancer while limiting side effects. The goal is to improve outcome…

This study looks at whether genetic information from tumors can help doctors choose the right treatment for pancreatic cancer. About 200 people with early or locally advanced pancreatic cancer will give blood and tissue samples while receiving standard chemotherapy. Researchers w…

This study is for men with early-stage prostate cancer who are getting a type of radiation called HDR brachytherapy. Researchers will use advanced lab tests to see how the radiation changes the tumor's chemistry and immune response. The goal is to find the best radiation dose wit…

This study looks at whether tailoring surgery for vulvar cancer based on the tumor's HPV and p53 status can reduce the chance of cancer coming back. About 249 women with early-stage vulvar squamous cell carcinoma will have their treatment guided by these markers. The goal is to a…

This study aims to understand how reading the full genetic code of a person's cancer can help doctors choose better treatments. Researchers will analyze tumor samples from 5,000 adults with advanced or metastatic cancers that cannot be cured. The goal is to match each cancer's un…

This study looks at how cancer patients feel and how long they live when given treatments that have some early promise but unclear overall benefit. Researchers will track 100 people with cancer to collect real-world information on quality of life and survival. The goal is to help…

This study looks at whether cancer patients can drink a radioactive sugar (called FDG) instead of getting it through an IV for a PET scan. About 27 adults who already had a standard PET scan will get a second scan using the oral method. Researchers want to see if the images are c…

This study looks at the genes of people with advanced pancreatic cancer to find patterns that might help choose better treatments in the future. Researchers will take a small sample of the tumor and analyze its DNA. They want to see if they can get the results back to doctors wit…

This study is for adults with rare cancers or rare genetic changes in their tumors who are already taking a targeted therapy approved by Health Canada but not yet publicly funded. The goal is to collect real-world information on how long patients live, their quality of life, and …