British Columbia Cancer Agency

This study tests a high-dose radiation implant (brachytherapy) for men whose prostate cancer returned after standard external beam radiation. About 30 participants will receive this targeted treatment to the exact spot of recurrence, identified by advanced MRI. The goal is to con…

This phase 2 trial tests whether giving prostate cancer radiation in just 2 sessions is as safe and effective as the standard 5-session approach. About 100 men with low- or intermediate-risk prostate cancer will be randomly assigned to one of the two schedules. Both groups will u…

This study compares standard moderate radiation (4 weeks) with shorter, more intense radiation schedules (1-2 weeks or a single session) for treating the prostate in men whose cancer has spread to a few other spots (oligometastatic). The goal is to see if the shorter treatments a…

This early-stage trial tests a new treatment called CLIC-2201 for people with B-cell cancers (like certain leukemias and lymphomas) that have come back or not responded to standard care. The treatment involves collecting a patient's own immune cells, modifying them to target a pr…

This study aims to see if matching the extent of surgery to the specific type of vulvar cancer (based on HPV infection and p53 gene changes) can reduce the chance of the cancer coming back. About 249 women with early-stage vulvar squamous cell carcinoma will take part. The goal i…

This study tests whether a precise, high-dose radiation technique called SABR works better than standard palliative radiation for people whose cancer has spread to a few new spots while on treatment. About 194 adults with solid tumors (excluding lymphoma or myeloma) and up to 5 g…

This study tests the immunotherapy drug atezolizumab in 200 people with advanced solid tumors (breast, lung, GI, and others). Researchers use each person's tumor DNA to see if it predicts a response. Participants get the same dose every 3 weeks. The goal is to see if DNA analysis…

This pilot study looks at whether closely monitoring and managing blood sugar levels can help people with pancreatic cancer. About 50 participants will wear a continuous glucose monitor during chemotherapy. Half will get intensive glucose management from an endocrinologist, while…

This study tests if a single, targeted radiation treatment works as well as the usual five treatments for early-stage breast cancer after lumpectomy. The goal is to make treatment easier for patients who live far from cancer centers. Sixty women aged 40 and older with small, earl…

This study explores whether cancer patients can drink a radioactive sugar solution instead of receiving it through an IV for PET scans. Researchers will compare image quality and find the best time to scan after drinking. About 27 adults who already had a standard PET scan will g…

This study looks at how a type of radiation called HDR brachytherapy changes prostate cancer on a molecular level. Researchers will analyze blood, tissue, and gut bacteria samples from 100 men with low-risk or early intermediate-risk prostate cancer. The goal is to find the best …

This study looks at whether genetic information from tumors can help doctors choose better treatments for pancreatic cancer. About 200 adults with early or locally advanced pancreatic cancer will receive standard chemotherapy and provide blood, tissue, and fluid samples for genet…

This pilot study is collecting real-world information from 100 cancer patients to better understand how treatments affect their quality of life and survival. Participants will fill out regular questionnaires about their well-being and undergo standard scans or lab tests every few…

This pilot study follows 30 adults with incurable rare cancers or rare genetic changes who are already taking a Health Canada-approved targeted therapy that is not publicly funded. Researchers will track quality of life, survival, and tumor response over time to generate real-wor…

This study looks at genetic changes in metastatic pancreatic cancer to see if they can help guide treatment choices. Researchers will take tumor biopsies and blood samples from 190 patients starting chemotherapy. The main goal is to see if genetic test results can be returned wit…

This study aims to understand advanced cancers by analyzing their complete genetic code. Researchers will take biopsies and blood samples from 5,000 participants to identify genetic 'drivers' of their cancer. The goal is to see if this information helps doctors choose more person…