New trial tests faster radiation for men with spread prostate cancer

NCT ID NCT04610372

Recruiting now Disease control Sponsor: British Columbia Cancer Agency Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares standard moderate radiation (4 weeks) with shorter, more intense radiation schedules (1-2 weeks or a single session) for treating the prostate in men whose cancer has spread to a few other spots (oligometastatic). The goal is to see if the shorter treatments are as well-tolerated and effective, while being more convenient and cost-effective. About 168 men who have not had prior prostate cancer treatment (except hormone therapy) will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (hypofractionated external beam radiotherapy, high dose rate brachytherapy, permanent seed implant, or stereotactic body radiotherapy)
What this could lead to: If successful, this could offer men with oligometastatic prostate cancer a more convenient and cost-effective radiation option with similar safety and quality of life.
What could go wrong: This is a Phase 2 trial with only 168 participants, so results may not apply to everyone. The shorter radiation schedules could have different side effects or be less effective in the long run.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OLIGOMETASTATIC PROSTATE CANCER

Contacts and locations

Locations

British Columbia Cancer Agency Center for the Southern Interior
RECRUITING

Kelowna, British Columbia, V1Y5L3, Canada
Fraser Valley Cancer Center
NOT_YET_RECRUITING

Surrey, British Columbia, Canada
Vancouver Cancer Center
RECRUITING

Vancouver, British Columbia, Canada
Vancouver Island Cancer Center
RECRUITING

Victoria, British Columbia, Canada

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