PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Clinical trials for PDAC - PANCREATIC DUCTAL ADENOCARCINOMA explained in plain language.
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New pill plus chemo takes on deadly pancreatic cancer in huge trial
Disease control Recruiting nowThis phase 3 trial tests a new drug called daraxonrasib, taken as a pill, either alone or with standard chemotherapy, against chemotherapy alone for people with metastatic pancreatic cancer. About 900 adults with confirmed pancreatic cancer that has spread will be randomly assign…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New pill plus chemo aims to tackle tough pancreatic cancer
Disease control Recruiting nowThis Phase 3 trial tests whether adding an experimental oral drug called atebimetinib to a modified chemotherapy regimen helps people with metastatic pancreatic cancer live longer. About 510 adults who have not had prior treatment will receive either the new combination or standa…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Immuneering Corporation • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New pill aims to keep pancreatic cancer away after surgery
Disease control Recruiting nowThis study tests a new drug called daraxonrasib in people with pancreatic cancer who have already had surgery and chemotherapy. The goal is to see if taking the drug can delay or prevent the cancer from returning compared to just watching and waiting. About 500 adults will be ran…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New hope for hard-to-treat pancreatic cancer: targeted drug combo enters phase 3 trial
Disease control Recruiting nowThis study tests whether adding an experimental drug called zoldonrasib to standard chemotherapy helps people with a specific genetic form of metastatic pancreatic cancer (KRAS G12D mutation) live longer without their cancer growing. About 670 adults with advanced pancreatic canc…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New pill targets KRAS cancers in early human trial
Disease control Recruiting nowThis early-phase trial tests an oral drug called ALTA3263 in about 448 adults with advanced solid tumors (like pancreatic, lung, or colorectal cancer) that have a KRAS mutation. The main goals are to check safety, find the right dose, and see how the body processes the drug. Part…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Alterome Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New pill targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-phase study tests a new drug called BBO-11818 in people with advanced cancers that have a KRAS mutation, including lung, pancreatic, and colorectal cancers. The main goals are to check safety and find the best dose, while also seeing if the drug can shrink tumors. Abou…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New smart chemo targets tumors, spares healthy tissue
Disease control Recruiting nowThis early-phase trial tests a new drug called AVA6103 in 174 people with advanced solid tumors (like pancreatic, stomach, or lung cancer) that have not responded to standard treatments. The drug is designed to activate only inside tumors, potentially killing cancer cells while r…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Avacta Life Sciences Ltd • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New hope for hard-to-treat cancers: targeted combo trial opens
Disease control Recruiting nowThis study tests a new oral drug, TNG462, combined with other treatments for people with pancreatic or non-small cell lung cancer that has lost the MTAP gene and, in some cases, has a RAS mutation. The trial has two phases: first to find the safest dose, then to see how well the …
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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Last-Resort drug access opens for advanced pancreatic cancer patients
Disease control AVAILABLEThis program offers daraxonrasib to adults with metastatic pancreatic cancer that has worsened after prior treatment and who have no other good options. It is for patients who cannot join ongoing clinical trials. The goal is to provide access to this experimental drug when no sta…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New hope for Hard-to-Treat cancers: experimental drug enters human trials
Disease control Recruiting nowThis early-stage study tests an experimental drug called TJ033721 (givastomig) in people with advanced or metastatic solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the right dose, and see how the body processe…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: I-Mab Biopharma US Limited • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Nanocell attack: new combo therapy takes on tough pancreatic cancer
Disease control Recruiting nowThis study tests whether adding specially designed nanocells (tiny particles that deliver a potent drug directly to cancer cells) to standard chemotherapy can help people with metastatic pancreatic cancer live longer. About 144 adults whose cancer has worsened despite prior treat…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Engeneic Pty Limited • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New combo therapy aims to slash deadly leaks after pancreatic cancer surgery
Disease control Recruiting nowThis trial tests whether giving three treatments together—two medicines and a surgical patch—can lower the risk of major complications after Whipple surgery for pancreatic cancer and other tumors. The study includes 400 high-risk patients with a small pancreatic duct. If successf…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE4 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Blood sugar control may boost chemo in pancreatic cancer
Disease control Recruiting nowThis pilot study looks at whether closely monitoring and managing blood sugar levels can help people with pancreatic cancer. About 50 participants will wear a continuous glucose monitor during chemotherapy. Half will get intensive glucose management from an endocrinologist, while…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New laser blood test could spot pancreatic cancer early
Diagnosis Recruiting nowThis study is testing a new laser-based blood test that uses nanoparticles to detect pancreatic cancer early. Researchers will enroll 400 people, including those with diabetes, pancreatic cysts, or pancreatic cancer, to see if the test can accurately identify cancer. The goal is …
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: Fondazione Policlinico Universitario Campus Bio-Medico • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC
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Blood test hunt for silent killer: 5,000 High-Risk volunteers sought
Diagnosis Recruiting nowThis study aims to see if adding simple blood tests and symptom reviews to standard screening can catch pancreatic cancer earlier in people with a high genetic risk. Researchers will enroll 5,000 participants who have certain gene mutations linked to pancreatic cancer. The goal i…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Could a simple breath test catch pancreatic cancer sooner?
Diagnosis Recruiting nowThis study is testing a non-invasive breath test to detect pancreatic cancer earlier. Researchers will collect breath samples from over 6,000 people who have been referred for possible pancreatic cancer. The goal is to see if the test can accurately identify the small number of p…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Diagnosis
Last updated Jun 27, 2026 12:35 UTC
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Simple breath test could spot pancreatic cancer sooner
Diagnosis Recruiting nowThis study aims to develop a non-invasive breath test to detect pancreatic cancer earlier. Pancreatic cancer is often diagnosed late because early symptoms are vague. The test measures tiny molecules in breath that may signal cancer. Researchers will collect breath and urine samp…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Imperial College London • Aim: Diagnosis
Last updated Jun 27, 2026 12:34 UTC
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New app aims to ease pancreatic cancer treatment journey
Symptom relief Recruiting nowThis study is testing a smartphone app called PDAC-PATHWAYS designed to provide information and support to people with pancreatic cancer who are about to start neoadjuvant therapy (treatment before surgery). The app includes educational modules and tools to help patients cope. Re…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC
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Lab-Grown 'Mini Tumors' could personalize pancreatic cancer care
Knowledge-focused Recruiting nowThis study aims to grow miniature versions of pancreatic tumors, called organoids, from small biopsy samples taken during routine endoscopic procedures. Researchers will check if these organoids match the genetic makeup of the original tumor. If successful, this approach could al…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: IHU Strasbourg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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5,000 volunteers needed to help detect pancreatic cancer sooner
Knowledge-focused Recruiting nowThis study enrolls 5,000 people at high risk for pancreatic cancer to donate blood, pancreatic juice, and medical images over 10 years. Researchers will use this information to develop and validate tests that can detect pancreatic cancer earlier, when it may be more treatable. Pa…
Matched conditions: PDAC - PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC