Last-Resort drug access opens for advanced pancreatic cancer patients

NCT ID NCT07573215

AVAILABLE Disease control Sponsor: Revolution Medicines, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 5 times

Summary

This program offers daraxonrasib to adults with metastatic pancreatic cancer that has worsened after prior treatment and who have no other good options. It is for patients who cannot join ongoing clinical trials. The goal is to provide access to this experimental drug when no standard therapy is available.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic adenosquamous carcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METASTATIC PANCREAS ADENOCARCINOMA PANCREATIC ADENOCARCINOMA PANCREATIC ADENOCARCINOMA METASTATIC PANCREATIC ADENOSQUAMOUS CARCINOMA PANCREATIC CANCER PANCREATIC CANCER METASTATIC PDAC PDAC - PANCREATIC DUCTAL ADENOCARCINOMA

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advent Health
AVAILABLE

Orlando, Florida, 32803, United States
Advent Health Shawnee Mission
AVAILABLE

Merriam, Kansas, 66204, United States
AdventHealth Porter
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Denver, Colorado, 80210, United States
Advocate Health Care
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Downers Grove, Illinois, 60515, United States
Alaska Oncology and Hematology
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Anchorage, Alaska, 99508, United States
Allegheny Health Network Cancer Institute
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Butler, Pennsylvania, 15212, United States
Allegheny Valley Hospital
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Natrona Heights, Pennsylvania, 15212, United States
Alliance Cancer Specialists
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Media, Pennsylvania, 19063, United States
Aurora Medical Center
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Grafton, Wisconsin, 53024, United States
Avera Cancer Institute
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Sioux Falls, South Dakota, 57105, United States
Baptist Health Lexington
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Lexington, Kentucky, 40503, United States
Baptist Hospital of Miami
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Miami, Florida, 33176, United States
Beth Israel Deaconess Medical Center
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Boston, Massachusetts, 02215, United States
Blessing Hospital
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Quincy, Illinois, 62301, United States
Blood and Cancer Center
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Canfield, Ohio, 44406, United States
Bon Secours St. Francis Cancer Center
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Charleston, South Carolina, 29414, United States
California Cancer Associates for Research and Excellence
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Fresno, California, 93720, United States
Cancer Care Northwest
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Spokane Valley, Washington, 99216, United States
Cancer Center of Kansas
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Wichita, Kansas, 67214, United States
Cancer and Blood Specialty Clinics
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Fountain Valley, California, 92708, United States
Care Oncology Center
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Chula Vista, California, 91911, United States
Carolina BioOncology Institute
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Huntersville, North Carolina, 28078, United States
Cedars-Sinai Medical Center
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Los Angeles, California, 90048, United States
City of Hope Cancer Center (California)
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Duarte, California, 91010, United States
City of Hope Chicago
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Zion, Illinois, 60099, United States
CommonSpirit
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San Luis Obispo, California, 93401, United States
CommonSpirit Oncology Mercy
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Durango, Colorado, 81301, United States
Compass Oncology
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Happy Valley, Oregon, 97223, United States
DHR Health
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Edinburg, Texas, 78539, United States
Dana Farber Cancer Institute
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Boston, Massachusetts, 02215, United States
Dartmouth Hitchcock Medical Center
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Lebanon, New Hampshire, 03756, United States
Deaconess Health System
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Newburgh, Indiana, 47630, United States
Desert Care Network Comprehensive Cancer
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Palm Springs, California, 92262, United States
Duke Cancer Institute
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Durham, North Carolina, 27710, United States
El Camino Health
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Mountain View, California, 94040, United States
Emory University Hospital
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Atlanta, Georgia, 30322, United States
Emplify Health by Gundersen
AVAILABLE

La Crosse, Wisconsin, 05461, United States
Endeavor Health Cancer Institute
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Naperville, Illinois, 60126, United States
Florida Cancer Specialists and Research Institute
AVAILABLE

Naples, Florida, 32746, United States
Fox Chase Cancer Center
AVAILABLE

Philadelphia, Pennsylvania, 19111, United States
Genesis Cancer and Blood Institute
AVAILABLE

Hot Springs, Arkansas, 71913, United States
Guthrie Sayre
AVAILABLE

Sayre, Pennsylvania, 18840, United States
Health Partners Oncology
AVAILABLE

Saint Paul, Minnesota, 55101, United States
Hematology & Oncology Associates of NEPA
AVAILABLE

Dunmore, Pennsylvania, 18512, United States
Hematology Oncology Associates of Fredericksburg
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Fredericksburg, Virginia, 22408, United States
Hematology Oncology Consultants
AVAILABLE

Royal Oak, Michigan, 48073, United States
Henry Ford Health
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Detroit, Michigan, 48202, United States
Hirschfeld Oncology
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Brooklyn, New York, 11206, United States
Holy Cross Health - Phil Smith Neuroscience Institute ALS Multidisciplinary Clinic
AVAILABLE

Orlando, Florida, 33308, United States
Honor Health
AVAILABLE

Scottsdale, Arizona, 85258, United States
Houston Methodist Hospital- Cancer Center
AVAILABLE

Houston, Texas, 77030, United States
Illinois Cancer Specialist
AVAILABLE

Arlington Heights, Illinois, 60005, United States
Intermountain Health
AVAILABLE

Denver, Colorado, 80211, United States
Jackson Oncology Associates
AVAILABLE

Jackson, Mississippi, 39202, United States
Johns Hopkins
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Baltimore, Maryland, 21231, United States
Kadlec Regional Medical Center
AVAILABLE

Kennewick, Washington, 99336, United States
Karmanos Cancer Institute (Barbara Ann Karmanos Cancer Hospital)
AVAILABLE

Detroit, Michigan, 48201, United States
LSU LCMC Health Cancer Center
AVAILABLE

New Orleans, Louisiana, 70112, United States
Lehigh Valley Hospital
AVAILABLE

Allentown, Pennsylvania, 18103, United States
Lynn Cancer Institute - Boca Raton Regional Hospital
AVAILABLE

Boca Raton, Florida, 33487, United States
MD Anderson Cancer Center
AVAILABLE

Houston, Texas, 77030, United States
MD Anderson at Cooper
AVAILABLE

Camden, New Jersey, 08103, United States
Marshfield Medical Center
AVAILABLE

Marshfield, Wisconsin, 54449, United States
Mayo Clinic - Arizona
AVAILABLE

Phoenix, Arizona, 85054, United States
Mayo Clinic - Florida
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Jacksonville, Florida, 32224, United States
Mayo Clinic Minnesota
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Rochester, Minnesota, 55905, United States
McFarland Clinic
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Ames, Iowa, 50010, United States
Medical College of Wisconsin
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Milwaukee, Wisconsin, 53226, United States
Memorial Cancer Institute
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Hollywood, Florida, 33021, United States
Memorial Sloan Kettering Cancer Center
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Long Island City, New York, 11101, United States
Mercy Hospital Fort Smith
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Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin
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Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City
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Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital St. Louis-South
AVAILABLE

St Louis, Missouri, 63128, United States
Methodist Richardson Cancer Center
AVAILABLE

Richardson, Texas, 75082, United States
Mid America Cancer Care
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Kansas City, Missouri, 64132, United States
Moffitt Cancer Center
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Tampa, Florida, 33612, United States
Montefiore Medical Center
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The Bronx, New York, 10461, United States
Monument Health Cancer Care Institute
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Rapid City, South Dakota, 57701, United States
Mount Sinai Medical Center of Florida
AVAILABLE

Miami Beach, Florida, 33140, United States
Mountain Health Clinic
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Natick, Massachusetts, 01760, United States
NHO Revive Research Institute
AVAILABLE

Lincoln, Nebraska, 68506, United States
NYU Langone Health
AVAILABLE

New York, New York, 10016, United States
Nebraska Cancer Specialists
AVAILABLE

Omaha, Nebraska, 68130, United States
New England Cancer Specialists
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Topsham, Maine, 04086, United States
New York Cancer and Blood Specialists
AVAILABLE

New York, New York, 11967, United States
NorthBay Health Heidi Y Campini Cancer Center
AVAILABLE

Vacaville, California, 95687, United States
Northwell Health
AVAILABLE

Lake Success, New York, 11042, United States
Northwest Georgia Oncology Centers
AVAILABLE

Marietta, Georgia, 30060, United States
Norton Cancer Institute
AVAILABLE

Louisville, Kentucky, 40217, United States
OSF Cancer Institute
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Peoria, Illinois, 61637, United States
Ohio Health
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Columbus, Ohio, 43214, United States
Oncology Hematology Associates
AVAILABLE

Springfield, Missouri, 65807, United States
Oregon Oncology Specialists
AVAILABLE

Salem, Oregon, 97301, United States
Overlook Medical Center - Medical Diagnostic Associates - Atlantic Medical Group
AVAILABLE

Morristown, New Jersey, 07960, United States
Owensboro Health Mitchell Memorial Cancer Center
AVAILABLE

Owensboro, Kentucky, 42303, United States
PanOncology Centre
AVAILABLE

San Juan, 00909, Puerto Rico
Park Nicollet Specialty Center
AVAILABLE

Saint Louis Park, Minnesota, 55426, United States
Piedmont Physicians Medical Oncology
AVAILABLE

Atlanta, Georgia, 30318, United States
Pratt Cancer Center
AVAILABLE

St Louis, Missouri, 63141, United States
Premier Health OH
AVAILABLE

Dayton, Ohio, 45459, United States
Premier Health OH
AVAILABLE

Middletown, Ohio, 45005, United States
Providence Medical Center
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Portland, Oregon, 97213, United States
Providence St. Mary Medical Center
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Walla Walla, Washington, 99362, United States
Riverside Health
AVAILABLE

Newport News, Virginia, 23320, United States
Rocky Mountain Cancer Center
AVAILABLE

Aurora, Colorado, 80012, United States
Saint Luke's Hospital of Kansas City
AVAILABLE

Kansas City, Missouri, 64111, United States
Sarah Cannon Cancer Institute
AVAILABLE

Nashville, Tennessee, 37203, United States
Seattle Integrative Cancer Center
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Renton, Washington, 98057, United States
Southern Cancer Center
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Daphne, Alabama, 36526, United States
Southern Cancer Center
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Mobile, Alabama, 36608, United States
St Luke's Cancer Institute
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Boise, Idaho, 83712, United States
St. Elizabeth Healthcare
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Edgewood, Kentucky, 41017, United States
Stanford University
AVAILABLE

Stanford, California, 94305, United States
Sutter Health
AVAILABLE

Sacramento, California, 95816, United States
Sutter Health
AVAILABLE

San Francisco, California, 94115, United States
Swedish Cancer Institute Treatment Center
AVAILABLE

Seattle, Washington, 98104, United States
Sylvester Comprehensive Cancer Center
AVAILABLE

Miami, Florida, 33136, United States
Tennessee Cancer Specialists
AVAILABLE

Knoxville, Tennessee, 37919, United States
Tennessee Oncology
AVAILABLE

Nashville, Tennessee, 37203, United States
Texas Oncology
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Pearland, Texas, 77584, United States
The Cancer & Hematology Centers
AVAILABLE

Grand Rapids, Michigan, 49546, United States
The Kaiser Permanente Medical Group
AVAILABLE

Roseville, California, 95661, United States
The Mount Sinai Hospital
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New York, New York, 10029, United States
The Queen's Medical Center
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Honolulu, Hawaii, 96813, United States
Thomas Jefferson University Hospital
AVAILABLE

Philadelphia, Pennsylvania, 19107, United States
Trinity Health Hospital
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Ypsilanti, Michigan, 48197, United States
UCI Health
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Orange, California, 92612, United States
UCLA Health Westlake Village
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Los Angeles, California, 90095, United States
UCSF John Muir Health
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Walnut Creek, California, 94598, United States
UH Seidman Cancer Centre
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Cleveland, Ohio, 44106, United States
USC Norris Comprehensive Cancer Hospital
AVAILABLE

Los Angeles, California, 90033, United States
USOR: Minnesota Oncology Hematology, PA
AVAILABLE

Edina, Minnesota, 55435, United States
UW Health Cancer Center at ProHealth Care
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Waukesha, Wisconsin, 53072, United States
University of Arizona Cancer Center
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Tucson, Arizona, 85719, United States
University of California
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Los Angeles, California, 90095, United States
University of California - San Francisco
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Oakland, California, 94158, United States
University of Chicago Medical Center
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Chicago, Illinois, 60637, United States
University of Iowa
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Waukee, Iowa, 50263, United States
University of Iowa Cancer Services Quad Cities
AVAILABLE

Bettendorf, Iowa, 52722, United States
University of Kansas Medical Center
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Westwood, Kansas, 66205, United States
University of Michigan
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Ann Arbor, Michigan, 48109, United States
University of Pennsylvania
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Philadelphia, Pennsylvania, 19104, United States
University of Vermont Medical Center
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Burlington, Vermont, 05401, United States
Utah Cancer Specialists (UCS)
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Salt Lake City, Utah, 84106, United States
Virginia Cancer Institute
AVAILABLE

Richmond, Virginia, 23229, United States
Virginia Cancer Specialists
AVAILABLE

Fairfax, Virginia, 22031, United States
Virginia Mason Medical Center
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Seattle, Washington, 98101, United States
Virginia Oncology Associates
AVAILABLE

Hampton, Virginia, 23606, United States
Washington University School of Medicine
AVAILABLE

St Louis, Missouri, 63141, United States
West Cancer Center
AVAILABLE

Germantown, Tennessee, 38138, United States
Willamette Valley Cancer Institute
AVAILABLE

Springfield, Oregon, 97477, United States
Yale New Haven Hospital
AVAILABLE

New Haven, Connecticut, 06519, United States
Zangmeister Cancer Center
AVAILABLE

Columbus, Ohio, 43219, United States

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